[1] Qiu HB, Cao SM, Xu RH. Cancer incidence, mortality, and burden in China: a time-trend analysis and comparison with the United States and United Kingdom based on the global epidemiological data released in 2020[J]. Cancer Commun (Lond), 2021, 41(10): 1037-1048. DOI: 10.1002/cac2.12197 [2] 徐向英, 曲雅勤. 肿瘤放射治疗学[M]. 3版. 北京: 人民卫生出版社, 2017: 5. Xu XY, Qu YQ. Radiation oncology[M]. 3rd ed. Beijing: People’s Medical Publishing House, 2017: 5. [3] 马天斌, 蒋振东, 俞海东, 等. 两种准直器宽度对鼻咽癌放疗中的剂量学差异影响[J]. 中国医学物理学杂志,2021,38(3):302-307. DOI: 10.3969/j.issn.1005-202X.2021.03.006 Ma TB, Jiang ZD, Yu HD, et al. Multileaf collimators of two different leaf widths in radiotherapy of nasopharyngeal carcinoma: a dosimetric comparison[J]. Chin J Med Phys, 2021, 38(3): 302-307. DOI: 10.3969/j.issn.1005-202X.2021.03.006 [4] 郭召. 动态多叶光栅准直器的技术现状及发展趋势[J]. 中国医疗设备,2021,36(1):154-158. DOI: 10.3969/j.issn.1674-1633.2021.01.035 Guo Z. Technical status and development trend of dynamic multileaf grating collimator[J]. China Med Devices, 2021, 36(1): 154-158. DOI: 10.3969/j.issn.1674-1633.2021.01.035 [5] 何自怀. 外挂电动多叶光栅实现调强放疗的研究[D]. 北京: 清华大学, 2016. He ZH. The study external dynamic multi-leaf collimator used for intensity modulated radiation therapy[D]. Beijing: Tsinghua University, 2016. [6] 陈高翔, 解传滨, 戴相昆, 等. 基于正交双层光栅的调强放射治疗临床应用[J]. 中国医疗设备,2021,36(4):81-85. DOI: 10.3969/j.issn.1674-1633.2021.04.019 Chen GX, Xie CB, Dai XK, et al. Clinical application of intensity modulated radiotherapy based on orthogonal dual‐layer MLC[J]. China Med Devices, 2021, 36(4): 81-85. DOI: 10.3969/j.issn.1674-1633.2021.04.019 [7] Varian Medical Systems. Millennium MLC system and maintenance guide[EB/OL]. (2019-10-11)[2022-11-16]. https://www.myvarian.com/s/productdocumentationdetail. [8] Fix MK, Volken W, Frei D, et al. Monte Carlo implementation, validation, and characterization of a 120 leaf MLC[J]. Med Phys, 2011, 38(10): 5311-5320. DOI: 10.1118/1.3626485 [9] Hernandez V, Saez J, Angerud A, et al. Dosimetric leaf gap and leaf trailing effect in a double-stacked multileaf collimator[J]. Med Phys, 2021, 48(7): 3413-3424. DOI: 10.1002/mp.14914 [10] Morris R, Laugeman E, Hilliard J, et al. Field-in-field breast planning for a jawless, double-stack MLC LINAC using flattening-filter-free beams[J]. J Appl Clin Med Phys, 2019, 20(11): 14-26. DOI: 10.1002/acm2.12722 [11] 李阔, 李成强, 祝婷, 等. Halcyon在30例鼻咽癌固定野调强计划中计划质量研究[J]. 中华肿瘤防治杂志,2021,28(8):612-615,636. DOI: 10.16073/j.cnki.cjcpt.2021.08.09 Li K, Li CQ, Zhu T, et al. Dosimetric study of nasopharyngeal carcinoma based on Halcyon accelerator fixed field inverse intensity modulation plan[J]. Chin J Cancer Prev Treat, 2021, 28(8): 612-615,636. DOI: 10.16073/j.cnki.cjcpt.2021.08.09 [12] 李成强, 陈进琥, 李振江, 等. 基于Halcyon和Trilogy固定野调强计划质量和执行效率应用研究[J]. 中华放射肿瘤学杂志,2019,28(1):57-60. DOI: 10.3760/cma.j.issn.1004-4221.2019.01.012 Li CQ, Chen JH, Li ZJ, et al. The dosimetric and delivery efficiency between Halcyon-and Trilogy-based IMRT plans[J]. Chin J Radiat Oncol, 2019, 28(1): 57-60. DOI: 10.3760/cma.j.issn.1004-4221.2019.01.012 [13] 李成强, 陶城, 陈进琥, 等. 一种新型加速器的乳腺癌固定野调强放射治疗中计划质量和执行效率评价[J]. 中华放射医学与防护杂志,2019,39(8):614-618. DOI: 10.3760/cma.j.issn.0254-5098.2019.08.010 Li CQ, Tao C, Chen JH, et al. The plan quality and delivery efficiency of intensity modulated radiotherapy on a new designed linac for left side breast cancer[J]. Chin J Radiol Med Prot, 2019, 39(8): 614-618. DOI: 10.3760/cma.j.issn.0254-5098.2019.08.010 [14] Tamura M, Matsumoto K, Otsuka M, et al. Plan complexity quantification of dual-layer multi-leaf collimator for volumetric modulated arc therapy with Halcyon linac[J]. Phys Eng Sci Med, 2020, 43(3): 947-957. DOI: 10.1007/s13246-020-00891-2 [15] Ding CX, Saw CB, Timmerman RD. Cyberknife stereotactic radiosurgery and radiation therapy treatment planning system[J]. Med Dosim, 2018, 43(2): 129-140. DOI: 10.1016/j.meddos.2018.02.006 [16] McGuinness CM, Gottschalk AR, Lessard E, et al. Investigating the clinical advantages of a robotic linac equipped with a multileaf collimator in the treatment of brain and prostate cancer patients[J]. J Appl Clin Med Phys, 2015, 16(5): 284-295. DOI: 10.1120/jacmp.v16i5.5502 [17] Tomida M, Kamomae T, Suzuki J, et al. Clinical usefulness of MLCs in robotic radiosurgery systems for prostate SBRT[J]. J Appl Clin Med Phys, 2017, 18(5): 124-133. DOI: 10.1002/acm2.12128 [18] 李益坤, 周彬, 曹晓卉, 等. TomoTherapy Hi. Art放射治疗系统故障分析与排除[J]. 医疗卫生装备,2020,41(1):106-108. DOI: 10.19745/j.1003-8868.2020025 Li YK, Zhou B, Cao XH, et al. Fault analysis and troubleshooting of TomoTherapy Hi. Art treatment system[J]. Chin Med Equip J, 2020, 41(1): 106-108. DOI: 10.19745/j.1003-8868.2020025 [19] 徐寿平, 王连元, 戴相昆, 等. 螺旋断层放疗系统原理及其应用[J]. 医疗卫生装备,2008,29(12):100-102. DOI: 10.3969/j.issn.1003-8868.2008.12.044 Xu SP, Wang LY, Dai XK, et al. Principle and application of helical tomotherapy[J]. Chin Med Equip J, 2008, 29(12): 100-102. DOI: 10.3969/j.issn.1003-8868.2008.12.044 [20] 吴皓楠, 胡彧. 医科达Synergy直线加速器多叶准直器工作原理和故障分析[J]. 中国医疗设备,2020,35(1):163-165,177. DOI: 10.3969/j.issn.1674-1633.2020.01.044 Wu HN, Hu Y. Operation principle and fault analysis of multi-leaf collimator in Elekta Synergy linear accelerator[J]. China Med Devices, 2020, 35(1): 163-165,177. DOI: 10.3969/j.issn.1674-1633.2020.01.044 [21] Hernandez V, Angerud A, Bogaert E, et al. Challenges in modeling the Agility multileaf collimator in treatment planning systems and current needs for improvement[J]. Med Phys, 2022, 49(12): 7404-7416. DOI: 10.1002/mp.16016 [22] Thompson CM, Weston SJ, Cosgrove VC, et al. A dosimetric characterization of a novel linear accelerator collimator[J]. Med Phys, 2014, 41(3): 031713. DOI: 10.1118/1.4866228 [23] Woodings SJ, Bluemink JJ, de Vries JHW, et al. Beam characterisation of the 1.5 T MRI-linac[J]. Phys Med Biol, 2018, 63(8): 085015. DOI: 10.1088/1361-6560/aab566 [24] Zhang K, Tian Y, Li MH, et al. Performance of a multileaf collimator system for a 1.5T MR-linac[J]. Med Phys, 2021, 48(2): 546-555. DOI: 10.1002/mp.14608 [25] International Commission on Radiation Units and Measurements. ICRU Report 83. Prescribing, recording, and reporting photon-beam intensity-modulated radiation therapy (IMRT)[R]. Bethesda: ICRU, 2010. [26] 林承光, 翟福山. 放射治疗技术学[M]. 北京: 人民卫生出版社, 2016: 142-143. Lin CG, Zhai FS. Radiation therapy technology[M]. Beijing: People’s Medical Publishing House, 2016: 142-143. [27] 朱健, 刘敏, 李建彬, 等. 多叶光栅静态调强技术对鼻咽癌放疗中危及器官受量的作用[J]. 中华放射医学与防护杂志,2009,29(2):171-173. DOI: 10.3760/cma.J.issn.0254-5098.2009.02.017 Zhu J, Liu M, Li JB, et al. Effect of multi-leaf collimator static intensity-modulated technique on dose to organs at risk in radiotherapy for nasopharyngeal carcinoma[J]. Chin J Radiol Med Prot, 2009, 29(2): 171-173. DOI: 10.3760/cma.J.issn.0254-5098.2009.02.017 [28] 陈欣, 李萌萌, 陈如君, 等. 局部晚期鼻咽癌静态调强、容积旋转调强和螺旋断层调强放射治疗的剂量学比较[J]. 中国医学装备,2022,19(3):17-22. DOI: 10.3969/j.issn.1672-8270.2022.03.003 Chen X, Li MM, Chen RJ, et al. Dosimetric comparison of sIMRT, VMAT and HT for locally advanced nasopharyngeal carcinoma[J]. China Med Equip, 2022, 19(3): 17-22. DOI: 10.3969/j.issn.1672-8270.2022.03.003 [29] 蔡佳利. sIMRT、VMAT和TOMO在鼻咽癌治疗中的剂量学研究[D]. 大连: 大连医科大学, 2019. Cai JL. Dosimetric study of sIMRT, VMAT and TOMO in the treatment of nasopharyngeal carcinoma[D]. Dalian: Dalian Medical University, 2019. [30] 蒋大振, 明淑凤, 陈改丽, 等. 鼻咽癌调强放射治疗锁野计划对低剂量区的影响[J]. 武汉大学学报(医学版),2020,41(5):746-749. DOI: 10.14188/j.1671-8852.2019.0547 Jiang DZ, Ming SF, Chen GL, et al. Impact of fixed-jaw field intensity modulated radiotherapy (IMRT) on low dose area of nasopharyngeal carcinoma[J]. Med J Wuhan Univ, 2020, 41(5): 746-749. DOI: 10.14188/j.1671-8852.2019.0547 [31] 黄霞, 苏坤普, 罗焕丽, 等. 铅门跟随与固定技术结合有无均整器模式的鼻咽癌IMRT剂量学比较[J]. 中国医学物理学杂志,2020,37(7):858-862. DOI: 10.3969/j.issn.1005-202X.2020.07.011 Huang X, Su KP, Luo HL, et al. Different intensity-modulated radiotherapy plans for nasopharyngeal carcinoma: a dosimetric comparison among JTT-FFF, JTT-FF, SJT-FFF and SJT-FF[J]. Chin J Med Phys, 2020, 37(7): 858-862. DOI: 10.3969/j.issn.1005-202X.2020.07.011 [32] 贾晓斌, 董晓庆, 岳堃. Jaw tracking模式下不同铅门阈值对鼻咽癌VMAT计划的剂量学和计划复杂度分析[J]. 中国医疗设备,2022,37(11):34-38. DOI: 10.3969/j.issn.1674-1633.2022.11.007 Jia XB, Dong QX, Yue K. Research on dosimetry and planning complexity of different Jaw threshold in VMAT of nasopharyngeal carcinoma based on jaw tracking technology[J]. China Med Devices, 2022, 37(11): 34-38. DOI: 10.3969/j.issn.1674-1633.2022.11.007 [33] 杨超凤, 钟胜河, 杨海明, 等. MLC类型不同的加速器对鼻咽癌调强放疗计划影响的研究[J]. 医疗卫生装备,2016,37(8):78-80. DOI: 10.7687/j.issn.1003-8868.2016.08.078 Yang CF, Zhong SH, Yang HM, et al. Effects of types of accelerators of MLC on IMRT plans of nasopharyngeal carcinoma[J]. Chin Med Equip J, 2016, 37(8): 78-80. DOI: 10.7687/j.issn.1003-8868.2016.08.078 [34] 刘聪, 李可孚, 杨永新, 等. 鼻咽癌调强放射治疗计划中两种规格多叶准直器的应用研究[J]. 右江医学,2022,50(10):759-762. DOI: 10.3969/j.issn.1003-1383.2022.10.008 Liu C, Li KF, Yang YX, et al. Application of two specifications of multi-leaf collimator in intensity modulated radiation therapy for nasopharyngeal carcinoma[J]. Chin Youjiang Med J, 2022, 50(10): 759-762. DOI: 10.3969/j.issn.1003-1383.2022.10.008 [35] 武星蕾, 吴爱东, 吴爱林. 准直器角度对鼻咽癌容积旋转调强计划及剂量验证的影响[J]. 中国医学物理学杂志,2019,36(11):1249-1254. DOI: 10.3969/j.issn.1005-202X.2019.11.002 Wu XL, Wu AD, Wu AL. Effects of collimator angles on planning and dose verification of volumetric modulated arc therapy for nasopharyngeal carcinoma[J]. Chin J Med Phys, 2019, 36(11): 1249-1254. DOI: 10.3969/j.issn.1005-202X.2019.11.002 [36] 贺先桃, 谭军文, 李钢, 等. 叶片运动限制参数对容积旋转调强放疗的影响[J]. 医疗卫生装备,2020,41(11):40-45. DOI: 10.19745/j.1003-8868.2020248 He XT, Tan JW, Li G, et al. Impact of constraint leaf motion parameter on volumetric modulated arc therapy[J]. Chin Med Equip J, 2020, 41(11): 40-45. DOI: 10.19745/j.1003-8868.2020248 [37] 黄娜, 王培, 张德康, 等. 应用AAPM标准模体评估MLC宽度对VMAT计划的影响[J]. 中华放射肿瘤学杂志,2016,25(4):376-380. DOI: 10.3760/cma.j.issn.1004-4221.2016.04.015 Huang N, Wang P, Zhang DK, et al. Influence of multileaf collimator leaf width on volumetric modulated arc therapy plans evaluated on AAPM standard phantom[J]. Chin J Radiat Oncol, 2016, 25(4): 376-380. DOI: 10.3760/cma.j.issn.1004-4221.2016.04.015 [38] Bortfeld T, Oelfke U, Nill S. What is the optimum leaf width of a multileaf collimator?[J]. Med Phys, 2000, 27(11): 2494-2502. DOI: 10.1118/1.1319524