长期低剂量核辐射接触人员机体相关指标变化

doi:10.13491/j.issn.1004-714X.2023.02.015

中国辐射卫生

2023, Vol. 32

Issue (2): 167-170 DOI: 10.13491/j.issn.1004-714X.2023.02.015

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长期低剂量核辐射接触人员机体相关指标变化

刘剑英¹, 尚伟华¹, 马得勋², 邱霞³, 刘书锋¹

1. 海军青岛特勤疗养中心，山东青岛 266071;
2. 海军青岛九七一医院，山东青岛 266071;
3. 明月海藻集团有限公司海洋食品加工与安全控制全国重点实验室，山东青岛 266400

Changes in body-related indices in people exposed to long-term low-dose nuclear radiation

LIU Jianying¹, SHANG Weihua¹, MA Dexun², QIU Xia³, LIU Shufeng¹

1. Qingdao Special Servicemen Recuperation Center of PLA Navy, Qingdao 266071 China;
2. PLA Navy NO.971 Hospital, Qingdao 266071 China;
3. State Key Laboratory of Marine Food Processing & Safety Control, Qingdao Brightmoon Seaweed Group Co., Ltd., Qingdao 266400 China

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摘要目的对核辐射低剂量长期接触人员进行抗氧化指标、免疫指标、淋巴细胞增殖活性和血生化等进行检测分析，探讨低剂量核辐射接触对机体的影响，为其辐射防护和职业健康监护提供依据。方法选取80名核辐射作业的人员为接触组，另选30名非接触人员为对照组，分别检测血生化、血清总抗氧化能力（T-AOC）、丙二醛（MDA）、谷胱甘肽过氧化物酶（GSH-Px）、超氧化物歧化酶（SOD）、淋巴细胞增殖活性、增殖细胞核抗原（PCNA）、细胞凋亡因子Bcl-2和Bax、淋巴细胞转化率、淋巴细胞微核率等指标。结果接触组T-AOC、GSH-Px、SOD、细胞增殖活性、PCNA、Bcl-2、淋巴细胞转化率、WBC、PLT与对照组相比明显降低；MDA、Bax与对照组相比明显增高，差异有统计学意义（P < 0.05）；淋巴细胞微核率二者比较无统计学意义（P > 0.05）。结论核辐射长期低剂量接触对作业人员相关指标有一定影响，但未造成明显损伤，核辐射接触人员应增强防护意识，加强科学防护，降低辐射损伤。

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	刘剑英
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关键词 ：核辐射接触人员, 辐射损伤, 细胞增殖活性, 淋巴细胞微核率

收稿日期: 2022-07-02

PACS:

X591

基金资助:军队后勤计划项目（AWS14C015;CJN15J001）

通讯作者: 刘书锋,E-mail:wf8439231@163.com E-mail: wf8439231@163.com

作者简介: 刘剑英（1969—），女，山东青岛人，主任医师，研究方向：辐射防护与健康维护。E-mail：ljy9586@163.com

引用本文:

刘剑英, 尚伟华, 马得勋, 邱霞, 刘书锋. 长期低剂量核辐射接触人员机体相关指标变化[J]. 中国辐射卫生, 2023, 32(2): 167-170.
LIU Jianying, SHANG Weihua, MA Dexun, QIU Xia, LIU Shufeng. Changes in body-related indices in people exposed to long-term low-dose nuclear radiation. Chinese Journal of Radiological Health, 2023, 32(2): 167-170.

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