CT引导下腔内联合徒手插植在宫颈癌根治性放疗中的应用

doi:10.13491/j.issn.1004-714X.2024.04.016

中国辐射卫生

2024, Vol. 33

Issue (4): 447-453,471 DOI: 10.13491/j.issn.1004-714X.2024.04.016

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CT引导下腔内联合徒手插植在宫颈癌根治性放疗中的应用

李阳, 刘梦雨, 尹萍, 李越, 朱晨静, 林丽, 张丝雨, 孙志华, 徐寒子

南京医科大学附属肿瘤医院(江苏省肿瘤医院)放疗科, 江苏南京 210009

Application of CT-guided intracavitary/freehand interstitial brachytherapy in radical radiotherapy for cervical cancer

LI Yang, LIU Mengyu, YIN Ping, LI Yue, ZHU Chenjing, LIN Li, ZHANG Siyu, SUN Zhihua, XU Hanzi

Department of Radiation Oncology, The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing 210018 China

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摘要目的探讨三维腔内联合徒手插植技术在宫颈癌根治性放疗中的临床应用价值。方法收集2019年4月—2021年9月于南京医科大学附属肿瘤医院采用CT引导下三维腔内联合徒手插植进行根治性放疗的宫颈癌患者的临床资料进行回顾性研究，分析短期疗效及不良反应，并以logistics风险回归模型评估影响短期疗效的独立预测因子。结果共计纳入182例患者，所有患者均顺利完成治疗，治疗结束3个月后，评估临床疗效发现治疗有效率达90.65%且在治疗期间下消化道3、4级不良反应发生率为4.4%；对IIIC期患者根据FIGO 2009标准重新分期并纳入影响分期的因素，发现患者近距离治疗前肿瘤体积是影响该期患者临床疗效的主要因素（P = 0.004）；结论作为宫颈癌根治性放疗中的关键手段，三维腔内联合徒手插植技术是安全有效的，可在地区肿瘤中心以外的基层院区快速普及开展宫颈癌近距离治疗。

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	李阳
	刘梦雨
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	朱晨静
	林丽
	张丝雨
	孙志华
	徐寒子

关键词 ：宫颈癌, 三维腔内联合徒手插植后装治疗, 短期疗效

收稿日期: 2024-03-19

PACS:

R816

基金资助:中华国际医学交流基金会肿瘤精准放疗星火计划临床研究（2019-N-11-12）；江苏省妇幼保健协会科研课题（FX202025）项目

通讯作者: 徐寒子，E-mail：xuhanzi@njmu.edu.cn E-mail: xuhanzi@njmu.edu.cn

作者简介: 李阳（1995—），江苏徐州人，住院医师，从事妇科放疗工作。E-mail：540232342@qq.com

引用本文:

李阳, 刘梦雨, 尹萍, 李越, 朱晨静, 林丽, 张丝雨, 孙志华, 徐寒子. CT引导下腔内联合徒手插植在宫颈癌根治性放疗中的应用[J]. 中国辐射卫生, 2024, 33(4): 447-453,471.
LI Yang, LIU Mengyu, YIN Ping, LI Yue, ZHU Chenjing, LIN Li, ZHANG Siyu, SUN Zhihua, XU Hanzi. Application of CT-guided intracavitary/freehand interstitial brachytherapy in radical radiotherapy for cervical cancer. Chinese Journal of Radiological Health, 2024, 33(4): 447-453,471.

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http://www.zgfsws.com/CN/10.13491/j.issn.1004-714X.2024.04.016 或 http://www.zgfsws.com/CN/Y2024/V33/I4/447

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