放疗中小野剂量测量技术进展浅析

doi:10.13491/j.issn.1004-714X.2024.04.022

中国辐射卫生

2024, Vol. 33

Issue (4): 483-490 DOI: 10.13491/j.issn.1004-714X.2024.04.022

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放疗中小野剂量测量技术进展浅析

令狐仁静^1,2, 张静^1,2, 梁润成^1,2, 陈法国^1,2, 赵日^1,2, 刘鑫^1,2

1. 中国辐射防护研究院, 山西太原 030006;
2. 核药研发转化与精准防护山西省重点实验室, 山西太原 030006

A brief analysis of the progress of small field dosimetry technologies in radiotherapy

LINGHU Renjing^1,2, ZHANG Jing^1,2, LIANG Runcheng^1,2, CHEN Faguo^1,2, ZHAO Ri^1,2, LIU Xin^1,2

1. Chinese Institute for Radiation Protection, Taiyuan 030006 China;
2. Shanxi Provincial Key Laboratory of Nuclear Drug R & D, Transformation and Precision Protection, Taiyuan 030006 China

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摘要相比于常规放疗射野，小野存在的高剂量梯度、带电粒子不平衡和源遮挡引起剂量效应等独特剂量学特点加大了剂量测量难度，临床剂量测量不确定度也相应增加，远超ICRU 24号报告中测量误差 < 5%的要求。近年来，随着新型放疗技术的发展，放疗技术射野最小可达mm级，大分割放疗单次照射剂量可至6 Gy以上，射野边缘剂量梯度更大，对剂量测量的准确性提出了更高的要求，精确的小野剂量测量技术已逐渐成为精准放疗领域研究热点。为确保测量结果具有更高的准确性，通过回顾国内外学者关于小野剂量测量方面的研究，梳理并总结小野剂量测量要点。本文介绍了小野剂量学特点，概述现阶段小野剂量测量技术及优化手段，包括探测器选型及探测器灵敏体积2方面的优化，并进一步对射野输出修正因子技术进行分析。针对小野剂量测量难等现状，结合临床需求及医用直线加速器等特点提出剂量测量建议，力争为放疗机构临床实践中的小野剂量测量提供科学参考，为放疗剂量验证的发展增注力量。

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	令狐仁静
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	刘鑫

关键词 ：放射治疗, 小野剂量, 探测器响应, 灵敏体积, 输出修正因子

收稿日期: 2024-03-20

PACS:

X591

基金资助:山西省基础研究计划（202203021222407）

通讯作者: 陈法国，E-mail：chenfaguo1@126.com E-mail: chenfaguo1@126.com

作者简介: 令狐仁静（1997—），女，山西太原人，研究生，从事小野剂量测量研究方向。E-mail：1422507655@qq.com

引用本文:

令狐仁静, 张静, 梁润成, 陈法国, 赵日, 刘鑫. 放疗中小野剂量测量技术进展浅析[J]. 中国辐射卫生, 2024, 33(4): 483-490.
LINGHU Renjing, ZHANG Jing, LIANG Runcheng, CHEN Faguo, ZHAO Ri, LIU Xin. A brief analysis of the progress of small field dosimetry technologies in radiotherapy. Chinese Journal of Radiological Health, 2024, 33(4): 483-490.

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http://www.zgfsws.com/CN/10.13491/j.issn.1004-714X.2024.04.022 或 http://www.zgfsws.com/CN/Y2024/V33/I4/483

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