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  • 28 June 2014 Volume 23 Issue 3
      
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  • Investigation and Analysis of Strontium Concentration of Drinking-water Surrounding Haiyang Nuclear Power Plant
    YANG Xin, CHEN Ying-min, XU Jia-ang, ZHANG Lin
    2014, 23(3): 193-197. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.03.001
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    Objective To investigate strontium concentrations of Drinking-water surrounding Haiyang nuclear powerplant, and make a analysis of the influencial factors of the strontium concentration; to assess the accumulated-effective dose of the residents surrounding nuclear power plant. Methods We choose 10 sample points, including surface water、groundwater and drinking water within 30 km surrounding Haiyang nuclear power plant in wet period and dry period,collecting 87 samples for all. The pretreatment and preparation of samples referred to the recommended methods of the national standards (GB 12375-90). The FJ2603G low background liquid β-spectrometer is used to measure the strontium concentration. Results The average level of the strontium concentration of water samples was (4.96 ±1.6) mBq·L-1,the range of the strontium concentrations was from 1.21~9.12 mBq·L-1. The difference of the strontium concentrations between two different periods analyzed by the paired t-test was considered non-statistically significant(P > 0.05). The orders of the average strontium concentration of various hydrographic period from high to low in drought period:tap water > ground water > surface water,as groundwater > tap water > surface water in high flow period. The accumulated-effective doses of groundwater、tap water、surface water which surrounding nuclear power plant were 0.104、0.103、0.095 μSv·a-1, respectively. Conclusion The activity concentration of strontium in the drinking-water surrounding Haiyang nuclear power plant was at the lower level than that of others'; according to the limited value that is regulated by basic standards for protection against ionizing radiation and fo the safety of radiation sources(GB 18871-2002) (1 mSv),the accumulated-effective dose which residents suffered was in background level of radiation.
  • Effects of MiRNA-22 Expression on the Radiosensitivity of Esophageal Squamous Cell Carcinoma
    QU Yuan, WANG Xiao-chun, CHE Yi-qun
    2014, 23(3): 198-200. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.03.002
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    Objective To study the effects of miRNA-22 expression on radiosensitivity of esophageal squamous cell carcinoma (ESCC). Methods Stable tranfected cell models with different miRNA-22 expression were builted. The changes of proliferation acitivity were measured by MTT and colony formation assay. Results The results of MTT and colony formation assay demonstrated that increased expression of miRNA-22 significantly inhibited the proliferation acitivity (P < 0.01) and sensitized ESCC cells to γ-ray radiation. Contrarily, decreased expression of miRNA-22 significantly promoted the proliferation acitivity (P < 0.01) and depressed radiosensitivity of ESCC cells. Conclusion These results demonstrated that the exprssion of miRNA-22 was associated with radiosensitivity of ESCC. Increased expression of miRNA-22 promoted the radiosensitivity of ESCC.
  • The Predictive and Diagnostic Role of miR-199b-5p in Osteosarcoma
    YANG Cheng, SU Hong-wei, REN Hui-wen, Li Hong-wei
    2014, 23(3): 201-204. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.03.003
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    Objective To identify the predictive and diagnostic role of miR-199b-5p in osteosarcoma. Methods Real-time PCR method was used to detect the expression of miR-199b-5p and DRAM in osteosarcoma. Bioinformation prediction tools were used to predict targeted genes of miR-199b-5p and analyze the relationship between miR-199b-5p and DRAM. Results Compared with the normal tissue, the level of miR-199b-5p was highly expressed in tumor tissues (P < 0.05); There was no significant relationship between miR-199b-5p and gender, ages, lesion,tumor site,types and stage (P < 0.05); DRAM and DRAM mRNA were expressed in different tissues. There was a negative correlation between DRAM andmiR-199b-5p. Conclusion Our results suggested that miR-199b-5p could function as the diagnostic marker. DRAM is probably the targeted gene of miR-199b-5p.
  • Radon Concentration and Other Parameters in Underground Hotwater of Chang'an District of Xi'an
    REN Lin, CAO Jian-ke, SHI Bin, LIU Jia-yi, MA Yang, LU Xin-wei
    2014, 23(3): 215-218. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.03.009
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    Objective Object Geothermal resource is very rich in central Shaanxi and is widely exploited presently. The object of the study is to know the effect of geothermal resource exploiting to indoor environment and people health. Methods The concentrations of radon and ions in geothermal water were measured by FD-125 Rn-analysis meter and Tracerlab crs-z-s ion analyzer, respectively. Results The measurement results indicat that the radon concentration is various in the geothermal water from different area and the radon concentrations in the water from Northwest University of Politics & Law, Luanzhen and fisheries of Dongdazhen are high with the maximum of 142.94 kBq·m-3. The ions concentration in the studied water samples are relatively high. Conclusion The usage of high radon geothermal water would cause radiation hazard to people and radon concentration is positive correlation with ion concentation. The radiation protection measurement of geothermal usage should be strengtherned.
  • Analysis in Control Level of Radionuclide Concentrations in Food and Water During a Nuclear Emergency
    YUAN Long, LEI Cui-ping, FU Xi-ming, WANG Zuo-yuan
    2014, 23(3): 244-247. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.03.023
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    Objective To analyze the control level of radionuclide concentrations in food and water during a nuclear emergency. Methods According to compares the number of radionuclides and their limitation values in food, milk and water from relevant international organizations, discuss our control level of radionuclide concentrations. Results After a nuclear or radiological emergency, the radionuclides released from the emergency could contaminate large area. In order to identify the degree of radio-pollution, the Food and Agriculture Organization of the United Nations, International Atomic Energy Agency and World Health Organization etc have published some publications in which the action level, intervention level and operational intervention action level etc were given and revised afterwards.,but our Standards are lagged. Conclusion According to the IAEA safety standard series ‘Criteria for Use in Preparedness and Response for a Nuclear or Radiological Emergency’, General Safety Guide No. GSG-2) and combined with our specific conditions, sincerely hope that our control level during a nuclear emergency will be revised.
  • The Study of the Influence of Air Flowrate on the Penetration of Iodine Traps and the Practical Application on Site Test
    HOU Jian-rong, LI Yong-guo, ZHANG Yuan, CHEN Jian-li, ZHANG Ji-rong, HAN Li-hong, QIAO Tai-fei, WU Bo, LIU Qun
    2014, 23(3): 252-255. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.03.026
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    Objective The relationship between the penetration (P) and air flowrate(Q) of iodine traps, is deduced from the analysis of the relationship between air flowrate and pressure of different type iodine traps. Methods By simulating different technical leak rates, the penetration and pressure of e iodine traps was tested with radioactive methyl iodine method. Results The test result verified the deduced relationship of P2=A/Q + B. Conclusion According to this relationship, a conservative penetration is got at a reduced air flowrate. The penetration of a series iodine traps banks of a nuclear power plant were tested by employing by-pass methods at a reduced air flowrate. It showed that it is a feasible way to test the penetration of iodine traps at special cases.
  • Investigation on Present Status of Occupational Hazard Factors in A Soda Ash Plant
    WANG Wei, CHENG Hu, ZHANG Fang, FENG Bin, YANG Shuang, WANG Rui
    2014, 23(3): 258-261. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.03.028
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    Objective To understand the occupational hazard factors in the production process and preventive measures in a soda ash plant, provide the basis for prevention and treatment of occupational diseases. Methods On-site occupational health investigation and detection of occupational hazards in the workplace were adopted to perform investigation and analysis on current status of occupational health. Results The main occupational hazard factors in the factory included dust, ammonia, sodium carbonate, carbon monoxide, hydrogen chloride, hydrogen sulfide, noise, high temperature. The exceeded rates were 21.2% for dust, 14.9% for ammonia, 13.8% for sodium carbonate, and 11.8% for noise. Hydrogen chloride, hydrogen sulfide and high temperature were up to the national health standards. Conclusion The protective measures and facilities of occupational hazards of this plant are feasible. The occupational health management system is relatively complete. But the indicators of some occupational hazard factors are high in this factory. It is necessary to improve the working environment, increase the protection degree and control the density and intensity of occupational hazard factors to prevent occupational disease.
  • The Clinical Observation of Clostridium Butyric Acid Retention-enema in the Prevention of Acute Radiation Proctitis
    XU Jing-jing, XING Yue-ming, WU Wei, XIAO Feng
    2014, 23(3): 262-264. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.03.030
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    Objective To observe the clinical efficacy of clostridium butyricum retention-enema to prevent acute radiation proctitis of cervical cancer. Methods 60 cervical cancer patients were randomly divided into combination group (30 cases) and single radiotherapy group (30 cases). All the patients received conventional radical radiation (extracorporeal irradiation and intracavitary therapy). The patients who are in combination group took clostridium butyricum retention-enema three times every-week before retiring while the other group just took radiotherapy alone during this time. Results Ⅰ degree of acute radiation proctitis incidence was 5/30 in combination group, and that of Ⅱ grade of acute radiation poctitis was 2/30. There is no Ⅲ degree of acute radiation proctitis. In the single radiotherapy group,the incidence rates ofⅠ,Ⅱ and Ⅲ grade of acute radiation poctitis were 16/30, 8/30 and 2/30. Comparing the two groups, the difference was statistically significant(P < 0.0001). Conclusion Clostridium butyric acid retention enema is an effective method of prevention of acute radiation proctitis.
  • The Observation on the Clinical Curative Effect of Breast Conserving Surgery with Adjuvant Radiotherapy in Breast Cancer
    ZHAI Jing, ZHANG Peng-cheng, GENG Kai, CAO Yong-zhen
    2014, 23(3): 270-272. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.03.035
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    Objective To observe the clinical effect of breast conserving surgery with adjuvant radiotherapy in breast cancer. Methods 62 cases of patients with breast cancer in our hospital from 2011 June-2013 June were selected randomly, and were divided into two groups,31 patients per group, breast conserving surgery with adjuvant radiotherapy in patients as study group, modified radical surgery with adjuvant chemotherapy as control group, analysis two group patients after treatment, cosmetic effect, therapeutic index, skin classification,and prognosis. Results The study group breast cosmetic results excellent rate of 77.42%, higher than 32.26% in the control group, significant differences with statistical significance (P < 0.05); and the research group of bleeding volume, operation time, less than the control group, significant differences with statistical significance (P < 0.05); at the same time case the number of each grade of two groups of skin reactions after radiotherapy, and the prognosis of patients with local recurrence rate, distant metastasis rate, survival rate is the difference was not statistically significant (P > 0.05). Conclusion Application of breast conserving surgery with adjuvant radiotherapy for breast cancer patients, significant effect, has a certain clinical value in research and application.
  • Clinical and Imaging Study on the Treatment of Lumbar Disc Herniation by Fixed-point Reposition and Crude Herb Moxibustion
    LIN Gang, ZHANG Bo
    2014, 23(3): 276-278. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.03.038
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    Objective To observe the effects of fixed-point reposition combined with crude herb moxibustion on lumbar disc herniation. Methods From September 2010 to June 2013, 624 patients with LDH were enrolled into the study. Among the patients, 326 patients were male and 298 patients were female, ranging in age from 12 to 78 years (averaged 48 years). Fixed-point reposition was used to resume mechanics balance of lumbar vertebra. Crude herb moxibustion was used on patients' pain part of lumbar vertebra and the acupoints. The total curative effects were evaluated. The clinical data of the patients were analyzed respectively, including visual analogue score (VAS) and Japanese orthopaedics lumbodorsal pain score (JOA). MRI or CT was used to measure the size and position of the protruded nucleus pulposus (size of disc protrution and the angle between nerve root canal and disc protrution). Results In the study, 342 patients were cured, 254 patients became better, and 28 patients were inefficient, with the total effective rate was 95.51%. VAS and JOA scores were improved after treatment (P < 0.01). No significant changes in the shape and size of protrude nucleus pulposus after treatment (P > 0.05). Conclusion It is worth clinical application and generalization that the good way treats lumbar disc herniation by using fixed-point reposition combined with crude herb moxibustion. However, the shape and size of protrude nucleus pulposus has no paralleled relation with clinical manifestations according to imaging study.