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  • 28 August 2014 Volume 23 Issue 4
      
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  • Forecast Analysis on Demand of Medical Workers in Sichuan Province Based on the ARIMA Model for Deploying the Nuclear Emergency Medical Resources
    HE Ling, WANG Meng-jie, LIU Fang, LI Jia-yuan, YANG Fei, GAO Yi-ying
    2014, 23(4): 289-292. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.04.001
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    Objective To forecast the demand of medical workers from 2014 to 2020 year by the data of medical workers in Sichuan province, and provide foundation for deploying the nuclear emergency medical technician resources rationally. Methods The demand of medical workers was analyzed and forecasted by the ARIMA(1,2,1) Model with Selecting the medical workers from the data during 1995-2013 from Sichuan Health Statistics Yearbook, Sichuan Statistical Year Book and Statistics Bulletin of Sichuan Statistics Bureau. Results It showed that the demand of medical workers in Sichuan province would rise smoothly, up to 649 700 in 2020 year. Conclusion It is suitable for forecasting the demand of the medical workers by ARIMA model. Then it should strengthen the efforts to train and bring in medical workers in order to deploy the nuclear emergency medical workers resources rationally and improve the nuclear medical emergency disploying capabilities.
  • A Study of Deformable Image Registration of Intensity Modulated Radiation Therapy CT Image to High-Dose-Rate Brachytherapy CT Image
    ZHEN Xin, CHEN Hai-bin, XIAO Yang, HU Jie, ZHOU Ling-hong
    2014, 23(4): 293-297. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.04.002
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    Objective To propose a novel method for theintensity modulated radiation therapy (IMRT) CT image to the high-dose-rate brachytherapy (HDR) CT image deformable image registration and dose accumulation. Methods The applicator in the HDR CT image is first segmented and removed, and the Demons algorithm is utilized to register the IMRT CT image to the deflated HDR CT image. The deflated applicator mask is used to locate the position of the vagina in the deformed IMRT CT image, and the vagina is then inflated using Demons. In this way, the IMRT CT image is finally registered to the HDR CT domain, along with the IMRT dose for dose accumulation. Results IMRT CT image and HDR CT image, as well as the corresponding IMRT dose and HDR dose, from the gynecologic cancer patients are used for the evaluation of the proposed method. The results show that our method can effectively get rid of the influence of the applicator and produce an accurate accumulated dose. Conclusions Dose accumulation and supervision are important steps in adaptive radiotherapy for accurate dose delivery and treatment plan re-optimization. This study proposes a novel method for IMRT-HDR CT deformable image registration and dose accumulation, and the accuracy is proved to be sufficient for clinical needs.
  • Geant4-based Simulation of the Energy and Angle Straggling of Proton on Thin Films
    ZHANG Hui, WANG Zhen-chao, GUAN Shi-rong, MEI Xue-song, LI-Xin
    2014, 23(4): 297-298,302. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.04.003
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    Objective Analysis of the relationship between the incident proton energy, target materials, the thickness of target materials and energy and angle straggling. Methods Using Geant4 program to simulate the incident proton energy of 100keV~10 MeV vertically into Be,C,H2O,Al,Cu film. Results Obtaining the relationship between the incident proton energy, target materials, the thickness of target materials and energy and angle straggling. Conclusion Energy straggling mainly occurs in the range of energy from 100keV to 200keV. The greater the thickness of target materials and the electron density of target material are, the greater the energy and angle straggling is. Energy and angle straggling is also associated with the incident proton energy. The general trend is the greater incident proton energy, the smaller the energy and angle straggling.
  • Study of Mutagen Sensitivity and the Risk of Developing Secondary Primary Tumors after Radiotherapy and/or Chemotherapy in Patients with Head and Neck Cancers
    QIN Jian, WANG Ren-sheng, MO Yao-xi, TENG Jia-an, YANG Hui-hua, LI Ting-ting
    2014, 23(4): 299-302. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.04.004
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    Objective To discuss the relationship between genetic stability and secondary primary tumor (SPT) after radiotherapy and/or chemotherapy in patients with head-and-neck cancers. Methods Compared bleomycin-induced chromatid breaks in peripheral blood lymphocyte cultures (as an indicator of latent genetic instability) between 67 cases (patients with SPT) and 47 controls (head-and-neck cancer patients without SPT). Results The time from the age of new diagnosis of head-and-neck cancer to SPT in SPT group was 16.73 ±6.31 (95% CI, 15.19~18.27) years, and to the last follow-up time in no-SPT group was 18.51 ±8.51 (95% CI, 16.01~21.01) years, respectively. The major tumor site and pathologic type of SPT was head-and-neck squamous carcinoma. The mean number of chromatid breaks per cell was significantly higher in SPT group 0.88 ±0.29(95% CI, 0.81~0.95) than in no-SPT 0.56 ±0.19(95% CI, 0.50~0.61) and the controls 0.52 ±0.18(95% CI, 0.46~0.58) (F=6.519, P=0.002). Low and high bleomycin sensitivity was determined by using 0.5 breaks/cell as a cutoff point. The high sensitivity ratio in SPT, no-SPT and control group were 85.07%, 65.96% and 52.50%, respectively (χ2=13.611,P=0.000). SPT as cases and others as controls, the area under ROC curve of the mean number of chromatid breaks per cell was 0.829, the standard error was 0.037 (P=0.000). The best cutoff point was 0.69. Conclusion The latent genetic instability is closely related with SPT in patients with head and neck cancers after radiotherapy and/or chemotherapy. The incubation period of SPT is as long as more than a decade. The mean number of chromatid breaks per cell is worth to estimate high risk of developing SPT in these patients. The optimal threshold value is 0.69, further verifications need be proceeding.
  • The Study of Radiation Dose for Doctor-Nurse in DSA Coronary Angiography
    SONG Yang, LI Zheng-cai, CHEN Shuo, HE Qiang, CHEN Da-wei
    2014, 23(4): 329-331. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.04.017
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    Objective To study the skin surface absorbed dose the interventional radiology physicians performing coronary angiography DSA, for and the interventional surgical procedure to analyze the radiation dose for the staff involved in the implementation of interventional surgery, and to provide some guiding suggestions for protection issues. Methods According to coronary angiography exposure conditions, Simulation phantoms equipped with thermoluminescent and dosimeters (TLD) were exposed by the DSA device in the condition same as the coronary angiography procedure, according to a standard mcarked curve, to measure the absorbed dose using BR2000D, of the high cayers the medical staff (first and second surgeon to surgeon) the absorbed dose of statistical analysis was performed using SPSS17.0 software. Results During coronary angiography, the first surgeon's eye lens, thyroid breast and gonad levels range are 0.261、0.301、0.226 and 0.243mGy, but these are 0.275、0.303、0.309和0.328mGy for the second surgery. Conclusion In the mobile under the action of lead screens, the skin surface absorbed dose of breast and gonad levels was significantly lower than those of the second surgeon, the range of the eye lens and thyroid levels of the a second surgery had no significant difference. In addition, interventional cardiologists, the first surgeon protective state is generally high degree of concern, for the second surgeon, protective measures should be strengthened further.
  • Spiral CT Scanning Neonatal Gonadal Radiation Protection Intervention Under Study
    LI Jie, TAO Ke-wei, JIN Ji-yang, GUO Xiao-li, XU Zhong-hua
    2014, 23(4): 332-334. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.04.018
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    Objective To measure, with light-induced opitical measuring techique, the interal and external radiation valcces to detect the protective effect of neonatal gonatal protection and the protective equipment under CT head scan. Methods With the photoluminescence measurements chip affixed to the inside and outside of neonatal gonadal protective equipment, radiation dose values were measured when CT scaing and the internal and external were compaired. Results The neonatal gonadal dose value of the unprotected parts is 0.115 mGy while the protective dose value of the protected pare is 0.041 mGy. Internal and external comparence shows 64% of the neonatal gonadal radiation dose was reduced when using the auxiliary protection, radiation dose was significant different(P < 0.05). Conclusion Neonatal gonadal site the values of the auxiliary CT radiation dose of the neonatal gonadal site may cause abnormal protection, The auxiliary protective device can effectively reduce the radiation dose values under the same condition.
  • Radiation Safety Evaluation for LA45 Medical High-energy Accelerator Test Site
    YANG Yong-xin, CHEN Ying-feng
    2014, 23(4): 346-349. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.04.025
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    Objective To evaluate whether LA45 medical linear accelerator test site comfroms to the requirements of radiation safety evaluation, the radiation dosages of the workers and the public were calculated, and evaluated according to the relevant standards. Methods The dosages produced from different types of rays were calculated during high-energy medical linear accelerator's testing based on NCRP 151, such as X-ray, electron beam, neutron ray, etc. Results The results showed that the effects of the site's radiation protection facilities' shielding protection could protect effectively the radiation safety of the workers and the public. Conclusion The application of Medical high-energy medical linear accelerator was still in infancy in China, the radiation risk was gradually increased accompanied with the ray energy's increasing. The evaluation methods for high-energy medical linear accelerator's radiation safety, which were provided in paper, could provide technical reference for the optimization of radiation protection.
  • Study on Measurment and Comparative Analysis of Tritium Oxide and Organic Tritium in Urine
    SU Feng, DI XiaoYun, Zhao Kai, BaiXue, YangJing
    2014, 23(4): 361-364. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.04.031
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    Objective To explore a fast, convenient and reliable sample preparation and measurement methods for staffs engaged in tritium. Methods The conventional distillation, potassium permanganate distillation, hydrogen peroxide bleaching, and persulfate oxidation method are used to do pretreatment of urine,then liquid scintillation measurements were made, all the results of the four measurements were analyzed. Results Among the above-mentioned four different urine samples measured after pretreatment of urine tritium,there was a significant difference in the results. Not all methods can be used for nuclear facilities, staff and related staff in vivo tritium of water and organic testing. Conclusion From the measurement accuracy in terms of potassium permanganate distillation, the method is suitable for the measurement of tritiated water; persulfate oxidation method is more suitable for the determination of the total tritium. To process rapidly processing large quantities of samples, you can use hydrogen peroxide oxidation method.
  • Experimental Validation for Analysis of Specific Activity of Natural Nuclides in Ores by Sourceless Efficiency Calibration Method
    Yan Wen-xun, Feng Ya-hui, Li Jian-jun, Zhou Cheng, Zheng Jian-ming, Cheng Wei, Dai Dong-qing, Zhang Xiu
    2014, 23(4): 365-367. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.04.032
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    Objective To verify the accuracy of the specific activity of natural nuclides in ordinary ores by sourceless efficiency calibration method(LabSOCS). Methods Standard point sources were used to verify the reliability for characterization of γ detector using LabSOCS, and standard ores volume source and non-standard ores volume source were used as experimental validation for analysis of specific activity of natural nuclides in ordinary ores by LabSOCS. Results LabSOCS can be applied to characterize the specific activity of natural nuclides in ordinary ores. Conclusion LabSOCS can be used as a supplementary method to efficiency calibration for analysis of specific activity of natural nuclides in ores.