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  • 28 December 2014 Volume 23 Issue 6
      
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  • Effect of 131I on the Spontaneous Incorporation of Thymocytes of 3H-TdR into mice
    ZHENG He, WANG Yan, WAN Shu-li, DONG YE Guang-zhi, MENG Qing-yong
    2014, 23(6): 481-483. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.06.001
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    Objective In the detection of different doses of 131I on the spontaneous incorporation of 3H-TdR in the mice thymocytes in vitro, to observe the effect of 131I on the spontaneous incorporation of 3H-TdR into mice thymocytes. Methods The same amount of 3H-TdR was given for the different spontaneous incorporation of 3H-TdR into thymocytes. Results Experiment in vitro shows that the value of CPM of the spontaneous incorporation of 3H-TdR into thymocytes in 131I (final concentration is 5Bq/ml) group is markedly higher than that of the normal thymocytes group. The value of CPM of the spontaneous incorporation of 3H-TdR into thymocytes in 131I (final concentration, 5×105Bq/ml and 5×106Bq/ml) group is lower than that of the normal thymocytes group. Conclusion Low dose of 131I had the stimulating effect in the spontaneous incorporation of 3H-TdR into thymocytes in vitro and large dose of 131I can significantly inhibit the spontaneous incorporation of 3H-TdR into thymocytes in vitro.
  • Values of MRI Scan in the Staging of Cervical Cancer
    YUAN Ling-qin, LI Wan-hu, LIU Nai-fu, CHEN Zhao-qiu, WANG Ying-ying, CHEN Yue-ting
    2014, 23(6): 483-485. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.06.002
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    Objective Our aim is to investigate the methods for the improvement of cervical cancer clinical staging. Methods We compared the coincidence rates of clinical staging and magnetic resonance imaging (MRI) staging with pathological staging using case control study. Results The accuracies of MRI staging was higher than that of clinical staging in both IB stage of cervical cancer (P < 0.05) and all cases (P < 0.01). Conclusion It is important to use MRI scan in the clinical staging in cervical cancer. Be careful in chosing surgical therapy when MRI shows that the outer cervix membrane is coarse or fuzzy.
  • The Effect of Thermotherapy Combined with Low-dose Irradiation on Hematopoietic and Immune Function of Mammary Carcinoma
    LIU Cheng-jun, ZHAI Rui-ren, PANG Zhao-xia, WANG Li
    2014, 23(6): 486-488,494. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.06.003
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    Objective To study the effect of thermotherapy combined with low-dose irradiation on hematopoietic and immune function of mammary carcinoma. Methods 40 mammary carcinoma patients were randomly divided into conventional chemotherapy group, thermotherapy group, low-dose irradiation group and combination therapy (thermotherapy plus low-dose irradiation) group. Cyclophosphamide 100 mg/m2 was administrated orally from day 1 to day 14, Methotrexate 40 mg/m2, 5-Fluorouracil 600 mg/m2 were administrated intravenously on 1th and 8th day. The same dose of Methotrexate and 5-Fluorouracil was qiver in low flow and maintain in the constant temperature for 120 minutes in Thermotherapy group. Mice were totally body irradiated by 0.01Gy/d of 60Co-γ ray for 5 days per week for 3 weeks in Low-dose irradiation group. The dose and method of thermotherapy and low-dose irradiation in combined therapy group were the same as in thermotherapy group and low-dose irradiation group. Peripheral blood, including white blood cell, red blood cell and platelet, the level of interleukin 2, interleukin 4, γ interferon, CD4+ T,CD8+ T were observed after the above treatments. Results The level of interleukin 2, interleukin 4, γ interferon, CD4+ T,CD8+ T in thermotherapy group, low-dose irradiation group and combination therapy group were significantly higher than that of the conventional group. The observed index in thermotherapy group and combined group was higher than that of the low-dose irradiation group (P < 0.05). Combined therapy group has a better result than the thermotherapy group, but there was no significantly difference between them (P > 0.05). The counts of white blood cell, red blood cell and platelet in the combined therapy group are higher than those of other groups (P < 0.05). Conclusion The combination of thermotherapy with low-dose irradiation has a better protective effect on the hematopoietic and immune function of mammary carcinoma patients.
  • Clinic Analysis of Bone Mineral Density and its Related Factors in Patients with Type 2 Diabetes
    YUAN Hang, ZHU Bao, WANG Jun-chao, XIAO Yi-chun
    2014, 23(6): 489-492. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.06.004
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    Objective To investigate the related factors for osteoporosis in patients with type 2 diabetes mellitus. Methods The bone mineral density (BMD) at lumbar vertebrae (L1-4),left femur neck, greater trochanter of femur and left Shaft of femur were measured by dual energy X-ray absorptiometry in 120 patients with type 2 diabetes mellitus. The patients were divided into three groups:normal group, osteopenia group and osteoporosis group. The correlations between BMD and age,course of disease, body mass index (BMI) and serumal indicators were analyzed by multivariate regression analysis. Results there were siginificantly statistical differences in age, course of disease,BMI,ALP,SNTX and 25-VitD between normal and osteoporosis group (P < 0.05), while there are differences only in course of disease between normal and osteopenia group. Logistic regression analysis showed that BMD of all those locum had independent correlation with age,BMI and 25-VitD, but also with course of disease except lumbar vertebrae. There was an negative correlation between ALP and BMD of all other locums except left Shaft of femur. Furthermore, SCTX and SNTX had an negative correlation with lumbar vertebrae and left Shaft of femur respectively. Conclusion In patients with type 2 diabetes mellitus,age, course of disease and low BMI are risk factors for osteoporosis, and it may be help ful to anticipate osteoporosis happening in future by detecting serumal 25-VitD,ALP,SNTX and SCTX.
  • Radiation Protection of Patients before and during Interventional Radiology Surgery
    ZHU Wei-guo, HOU Chang-song, LIAN De-xing, LIU Chang-an
    2014, 23(6): 496-500. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.06.007
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    Objective To analyze the key point influence patient dose before and during the interventional radiology surgery, explore the radiation protection of patients before and during the surgery. Methods The implementation process of interventional radiology analysis and access to relevant literature, research interventional radiology surgery patient dose control methods. Results Patients should pay attention to many aspects of radiation protection effects and multiple dose data concerns surgery available. Conclusion Preoperative rational planning and improve intraoperative patient dose management and control is an effective way to reduce the absorbed dose.
  • The Clinical Application of Low-Dose CT imaging in Coronary Artery Angiography
    LIU Quan-yuan, DU Hai-ling, ZHANG Di, WANG Jing, LIU Wei
    2014, 23(6): 517-519. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.06.017
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    Objective To study the feasibility of low dose CT imaging in coronary artery and the relationship with image quality, to reduce the radiation damages to patients as far as possible. Methods 60 patients with clinical suspicion or diagnosis with coronary heart disease were selected and divided into group A and group B, each group of 30 cases. Group A was scanned with a regular doses protocol of 650 mA and group B with low dose of 450 mA. Image quality, image noise, CTDIvol, DLP and effective dose were compared and evaluated. Results The scores of images quality were 3.56±0.43 and 3.52±0.63 for group A and group B, respectively, wihle the image noise were 29.62±4.24 and 27.32±5.21. All of the images obtaining from the two doses protocol met the diagnostic requirements. There was no statistical significance between the two groups. However, the CTDIvol, DLP, E of low dose protocol just accounted for 49.53%, 49.53% and 49.55% of the regular doses protocol, respectively. Conclusion Image quality of coronary artery scanning with a 30% reduction of regular mA was not bad, but the radiation dose of patients and the radiation damages of the public crowd could be significantly reduced. Human health would be protected.
  • Osimetric Comparision and Analysis of Two Kinds of Intensity-Modulated Plan for Nasopharyngeal Carcinoma (NPC)
    ZHAO Zeng-jun, WANG Jian-bo, CHENG Yu-feng, LI Qi-xin
    2014, 23(6): 525-528. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.06.020
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    Objective To compare IMRT with VMAT for NPC patients with regard to the sparing effect on organ at risk (OAR), dosimetric quality,treatment delivery time and monitor units (MUs). Methods Fifteen patients with NPC were planned by IMRT and VMAT for dosimetric comparison. Results For most parameters such as HI CI Dmeans and D1% in target area, the results of VMAT plans were better than those of IMRT plans. In OAR, although for Dmeans of brain stem and D1% of optic nerves and right lense, there were no significant difference between VMAT and IMRT, VMAT plans had a better sparing effect for most parameters. The delivery time per fraction for VMAT (4.1 min) was much shorter than the time for IMRT (8.8 min). Compared to IMRT (823.5 MUs), VMAT (597.7 MUs) reduced Mus by 37.8%. Conclusion The results indicate that IMRT plan and both VMAT plan could have similar target coverage and meet clinical needs,however for most parameters in target area and OAR, the results of VMAT plans were better than these of IMRT plans, particularly on HI and CI of target and to protect OAR such as brain-stem spine-cord and parotid, but VMAT plans were as if not enough to protect small volume OAR such as optic nerve, optic chiasma and lense. VMAT provided shorter delivery time per fraction and fewer monitor units than IMRT.
  • Low Dose MSCT Three-Dimensional Standard Measurement Technology in the Protection Value of Lung Biopsy
    ZHANG Kong-yuan, LI Xian-jun
    2014, 23(6): 529-531. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.06.021
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    Objective To explore the application of low-dose CT-guided electroanatomic PV in lung puncture biopsy of puncture technique to reduce effective dose value. Methods Select 100 cases in need of line lung puncture andrandomly divide them into two groups with 50 cases as experiment group using low dose CT positioning technology and three dimensional marked measuring technology line lung puncture biopsy, while the controlled group using General CT positioning and existing General puncture technology. Records their times of puncture and positioning CT scan and calculate the received effective dose. Comparison was made between the two groups in t test. Results Experiment group's puncture is (1.26±0.53) times, CT positioning scan, (3.28±0.57) times. patients of received total effective dose is (1.27±0.32) mSv; control group puncture time is (4.44±1.82) times, CT positioning scan time is 6.24±1.82, patients' total effective dose received is (14.05±4.26) mSv; In comparison of experimental and control groups, the difference in puncture time is statistically significant (t=11.87, P < 0.05), the difference of CT localization scanning times is statistically significant (t=11.64, P < 0.05), the differenceof the total effective dose is statistically significant (t=21.16, P < 0.05). Conclusion Electroanatomic puncture technique, may improve the accuracy of puncture andreduce the times of puncture in a successful biopsy and the times of CT positioning technology can greatly reduce the total dose received by the patients.
  • HEPA Leak Rate Testing Study For PAO4 In Nuclear Ventilation System
    ZHANG Ji-rong, HOU Jian-rong, LI Yong-guo, SHI Ying-xia, ZHANG Qun, CHEN Jian-li, LIANG Fei
    2014, 23(6): 557-559. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.06.033
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    Objective To overcoming the pungent smell when DOP generates aerosol and the risk of potential carcinogen for HEPA leak rate testing in nuclear ventilation system. Methods The closed cup method is used to measure the flash point about PAO4 and DOP. Mixing uniformity testing and in-site leak rate testing are done according to the EJ/T 791standard. Results The flash point of PAO4 is higher than the flash point of DOP. It is stable when PAO4 generates aerosol. The leak rate testing result is coincident. Conclusion PAO4 is deserved to popularize for HEPA leak rate testing in nuclear ventilation system.
  • Manifestation and Diagnosis of MRI for Deep Anorectal Abscess
    FU Qi-tian, CHEN En-ming, TENG Bi-he, MA Zhou-peng
    2014, 23(6): 560-562. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.06.034
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    Objective To explore the MRI performance and diagnosis value of deep anorectal abscess. Methods The clinic and MRI data of 26 cases of deep anorectal abscess proved by clinic,surgery and pathology were analyzed retrospectively. Results Among 26 cases,29 deep anorectal abscesses were detected, 23 showed single antrum,6 showed multi-antrum. 16 were isehiorectal abscesses, 9 were pelvirectal abscesses, and 4 were high intersphineterie abscesses. the cavity of abscess showed symmetrical or asymmetry low signal on T1WI and T2WI and DWI showed obvious high signal, The wall of abscess showed equal signal or asymmetry mild low signal on T1WI and T2WI and DWI showed mild high signal. On dynamic enhanced MR,the wall of abscess and compartmentation of multi-antrum showed continuous obvious enhancemen. The accurate ratio of locative diagnosis was 100% (26/26) and the accurate ratio of qualitative diagnosis was 92.3% (24/26). Conclusion MRI can show the anatomic structure of deep anorectal abscess and rectum and anus together with the signal of the wall and cavity of abscess clearly. It can provides important value for surgical planning and operation, and is important for the diagnosis for deep anorectal abscess.
  • Value of Dynamic Defecography in Patients with the Spastic Pelvic Floor Syndrome
    TIAN Ning, SHAO Guang-rui, ZHANG Xin-yi, SUN Yan
    2014, 23(6): 570-573. https://doi.org/10.13491/j.cnki.issn.1004-714x.2014.06.039
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    Objective To evaluate the role of dynamic defecography in diagnosis patients with the Spastic Pelvic floor syndrome. Materials and methods:The images of defecography in 44 cases of anismus and 22 volunteers were retrospectively analyzed. Methods The anorectal angle (ARA) at quiescent and defecation, and the difference between them was calculated. T test was used in statistical analysis. Results 21 patients with spastic pelvic floor syndrome (SPFS) also suffered from rectocele, anterior mucosal prolapse or other disease. The ARA in patients group at quiescent,defecation and difference between them were (103.2±8.62)°, (92.8±7.38) ° and (10.4±7.9)° respectively, and those in normal control group were (117.4±12.7)°, (137.1±10.4) ° and (19.7±12.4)° respectively. There was significant difference in ARA between two groups (P < 0.01). Conclusion Dynamic defecography can provide reliable diagnostic basis for the Spastic Pelvic Floor syndrome.