Archive

  • 28 June 2013 Volume 22 Issue 3
      
  • Select all
    |
  • The Observation of Neoadjuvant Radiiotherapy for Stage Ⅱ Cervical Carcer
    XING Yue-ming
    2013, 22(3): 257-259,262. https://doi.org/10.13491/j.cnki.issn.1004-714x.2013.03.053
    Download PDF ( ) HTML   Knowledge map   Save
    Objective Collect the 3-years and 5-years survival rates of Ⅱ cervical carcer treated by neoadjuvant radiotherapy plus radical surgery to analyse the impact of neoadjuvant radiotherapy on surgery and observe the side effects of radiotherapy to discuss the value of neoadjuvant radiotherapy to stage Ⅱ cervical cancer. Methods 109 stage Ⅱ cervical cancer patients were chosen in the No. 2 Hospital of Shanxi Medical University during July 2007 to April 2011. Group 1(n=59) received the preoperative neoadjuvant radiotheerapy (external beam radiation therapy and intracavitary brachyteerapy). After a rest of 2 to 3 weeks, radical hysterectomy wity pelvic lymphadenectomy was performed. Group 2(n=50) underwent radical radiation therapy alone. Results ①There was no significant difference between 3-years and 5-years survival tates between neoadjuvant radiotherapy group and radical radiotherapy group for the short-term follow-up. ②59 patients successfully received radical surgery without increasing the rate of complications. ③Major radiotherapy side effects in neoadjuvant radiotherapy group occurred less frequently than the in radical radiotherapy group(P < 0.05). Conclusion ①Neoadjuvant radiotherapy can decrease the tumor volume and even disappeared and improved the rate of resection. And indication of operation was extended. ②Neoadjuvant radiotherapy didn't increase the surgical difficulties and complications. ③Compare of radical hysterectomy, Neoadjuvant radiotherapy can reduce the short-term radiation side effects and long-term complications. ④ Neoadjuvant radiotherapy can depressed the viability of the cancer cells and reduced the chance of neoplasm metastasis. ⑤ Compare of radical hysterectomy, Neoadjuvant radiotherapy can get similar or more higher the long-term survival.
  • Study on Multi-Spiral CT Angiography in Heptic Arteries
    OUYANG Ai-mei, SU Xin-you, JIA Shu-li, WEI Zhao-long, LI Shu-jing, MA Xiang-xing
    2013, 22(3): 260-262. https://doi.org/10.13491/j.cnki.issn.1004-714x.2013.03.041
    Download PDF ( ) HTML   Knowledge map   Save
    Objective To investgate the possibility of fixed delay time multi-spiral CT imaging hepatic arteries (MSCTA); To optimize the best imaging method and the delay time on 16-slice MSCTA in hepatic arteries. Methods 380 patients who underwent multiphase enhanced liver scan were divided into 6 groups randomly. All groups completed by 16-slice CT according to different delay time (20 s, 25 s,30 s), injection flow rate (3.0 ml/s, 3.5 ml/s), reconstruction layer thickness (0.75 mm, 2 mm) and scanning methods (fixed delay time and automatic trigger technology). Display effect on hepatic arteries were analyzed. Results The best delay time of hepatic arteries in 16-slice CT was 25 s respectively. Differences between 0.75 mm and 2 mm thick layer of reconstruction were statistically significant. There were no difference between 3.0 ml/s group and 3.5 ml/s group,so it was between fixed delay time and automatic trigger. Conclusion Fixed delay time MSCTA in hepatic arteries was applicable for clinical use.
  • Immobilization and Setup Error Study for Thoracic Cancers Radiotherapy
    YAN Hua-wei, JIN Xian-ce, ZHOU Yong-qiang, YANG Gui-qiang, WU Zhi-qaing, PAN Han-hui, XIE Cong-ying
    2013, 22(3): 263-266. https://doi.org/10.13491/j.cnki.issn.1004-714x.2013.03.055
    Download PDF ( ) HTML   Knowledge map   Save
    Objective To study the setup errors of three immobilization methods in thoracic cancer radiotherapy with cone beam CT. Methods Setup discrepancy in R/L, S/I, and A/P directions were calculated and recorded after CBCT scan with Elekta XVI. Residue errors after correction was recorded with second CBCT scan. Total errors were also calculated. Results Setup errors were significantly reduced after CBCT correction. Group with thermoplastic frame indicated the least residue setup errors compared to the other two immobilization methods (P=0.06). Conclusion Setup correction with CBCT can reduce the setup error dramatically for thoracic cancer radiotherapy. Thermoplastic frame achieved best setup accuracy with CBCT correction.
  • Study of Differential Gene Expression Profiling in Rat Peripheral Blood Lymphocyte 12 Hours after in-vitro and Whole-body Exposure to 2Gy Gamma Ray
    YIN Jing-jing, QIN Xiu-jun, ZHANG Wei, YUAN Hui, LI Jian-guo, WEN Jian-hua
    2013, 22(3): 267-269. https://doi.org/10.13491/j.cnki.issn.1004-714x.2013.03.001
    Download PDF ( ) HTML   Knowledge map   Save
    Objective To evaluate the changes of differential gene expression in peripheral blood lymphocyte of SD rats 12 hours after in-vitro and whole-body exposure to 2Gy 60Co γ-ray, and provide the evidence for irradiation damage in gene level. Methods The method of microarray was applied to detect the differentially expressed genes and analyze the pathways. Gene expression was measured using real-time quantitative PCR to validate the results of the microarray. Results The results showed that there were 2 001 genes differentially expressed over 3 fold in in-vitro group, 2 590 genes in whole-body group, and 312 genes in both in-vitro and whole-body groups differentially expressed. There were 22 KEGG pathways in in-vitro group, 35 KEGG pathways in whole-body group, and 10 KEGG pathways in both. The relative quantity's results of three genes, selected to validate the microarray, were consistent with microarray results. Conclusion These results indicate that the differentially expressed genes are related to apoptosis, cell cycle and signal transduction etc, which will provide a basis for the further study of mechanism of irradiation damage.
  • Reducing Radiation Dose During Routine Brain CT using Helical with Tube Current Modulation Mode
    FU Qiang, NIU Meng, LIU Xiao-Fei
    2013, 22(3): 270-273. https://doi.org/10.13491/j.cnki.issn.1004-714x.2013.03.046
    Download PDF ( ) HTML   Knowledge map   Save
    Objective To determine whether radiation dose can be reduced and image quality improved in routine head CT that were acquired with organ-based tube current modulation (TCM) technology. Methods In a prospective study 50 adults patients scheduled for head CT used in both the routine axial and helical with TCM modes. Scan parameter:TCM mode were 120 kVp, 280 mA(Max mA threshold value), scan time 0.8s/rol. the manual mode were 140 kVp, 170 mA for petrou bone, and 120 kVp, 150 mA for brain, scan time 2.0s/rol. Radiation dose were measured directly from the CT scan indicated(CTDI and DLP). The image quality at the level of the posterior fossa and grey-white matter contrast and overall image were assessed by two readers using CT value and signal-to-noise ratio(SNR) detected, Reading orders were randomized. Results Compared the routine axial scan mode,The TCM scan mode reduced tube current (44 ±12) mA, exposure time (4.8 ±0.8) s, radiation dose (38 ±0.9)%[CTDI:(32.10 ±9.0) mGy,(55.00 ±7.2) mGy; DLP (442.10 ±72) mGy ·cm,(668.00 ±26) mGy·cm]; The effective radiation dose is reduced by (1.5 ±0.4) mSv, respectively. The image quality was effectively improved. Conclusion Routine head CT scan using helical with TCM scan mode has reduced the superiority of the scan time and radiation dose. The image quality can comparable to routine axial scan mode.
  • A Survey and Analysis on Radiological Protection Knowledge Guided by Knowledge-Attitude-Practice Model
    Cao Lei, Tu Yu
    2013, 22(3): 344-346. https://doi.org/10.13491/j.cnki.issn.1004-714x.2013.03.029
    Download PDF ( ) HTML   Knowledge map   Save
    Objective This article aims to investigate the status of the radiological protection knowledge, attitude and practice within three main areas. Method Posters,brochures and questionnaire were designed to educate the audiences, 145 in total were involved in this investigation while research procedure focuses three steps:first is cross-section survey on baseline status, second is education process implementation, final step is result evaluation. Results Knowledge against radiological protection varies according to different factors, outcome from education shows significant difference (P < 0.01) after education. Conclusion As shown from baseline study, public audience has very limited knowledge of radiological protection, but easy to accept basic knowledge; guideline for radiation related jobs should also be implemented to protect the patient and healthcare staff.
  • Application of Body Membrane Method with Double Labeling in Intensity-Modulated Radiotherapy after Breast-Conserving Surgery
    LI Ya, ZHAO Biao, ZHANG Ming, ZHAO Chun-fang, YANG Yi
    2013, 22(3): 365-367. https://doi.org/10.13491/j.cnki.issn.1004-714x.2013.03.052
    Download PDF ( ) HTML   Knowledge map   Save
    Objective To observe applying of body membrane method with double labeling in intensity-modulated radiotherapy after breast-conserving surgery. And discuss its clinical value. Methods Thirty patients with breast cancer, who received breast-conserving surgery were divided into group A and group B, each in 15. Common body membrane method was used in group A; body membrane method with double labeling was applied in group B. Reduplicative setup error was measured by simulation location machine in left-right head-foot anterior-pone breast. Results Setup error and shift error of silver clip is obvious in group A. Relatively, setup error and shift error of silver clip is extremely trifling in group B. Two groups were of statistically significant difference(P < 0.05). Conclusion Body membrane method with double labeling, simply used, improved accuracy and reduced setup error. The method is important on QA and QC of intensity-modulated radiotherapy with body membrane method after breast-conserving surgery.