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  • 28 April 2016 Volume 25 Issue 2
      
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  • Study of Calibration the Dosemeter for Measuring Eye Lens Dose in Terms of HP(3) with Different Phantom
    LI Hai-liang, WANG Zhong-wen, ZHU Jian-guo, XU Jia-ang, YANG Ying-xiao, ZHANG Lin, LI Fu-shen
    2016, 25(2): 129-133.
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    Objective To calibrate the dosemeter for measuring eye lens dose in terms of HP (3) and study the performance of the dosemeter,such as batch homogeneity,detection threshold,linearity,energy response,isotropy.Methoods The standard for calibration is based on ISO 12794(2000),phantoms are slab phantom and cylindrical phantom,radiation quality is the narrow beam X-ray (N60~N120) taken from ISO 4037.Results The performance of the dosemeter,as batch homogeneity,the coefficient of variation is 5.7%.The detection threshold is less than 0.1 mSv.As linearity,for two phantoms,response are both less than 10%.The energy responses to both phantoms,are in the range of 20%~40%.As isotropy,mean value of the response differ from the response of normal incidence is (1.05±0.03) for the slab phantom,and (0.99±0.08) for the cylindrical phantom.Conclusion For selected experimental conditions,both phantoms are suitable for eye lens dosemeter calibration,the calibration results conform to the requirements of ISO 12794,the dosemeter is suitable for using in interventional radiology.
  • Comparison of the Spine Tracking Accuracy between Supine and Prone Position Setups in CyberKnife Treatment
    XU Hui-jun, DUAN Xue-zhang, Xu Fei, Zhang Jun-hua
    2016, 25(2): 133-135.
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    Objective Using head and neck, anthropomorphic and lung phantoms to detect the spine tracking accuracy during CyberKnife IGRT treatment, compare the results in supine and prone positions and analyze them, to provide theoretical foundation for the application of supine position in spine tracking system.Methods Scan with CT the head and neck phantom with films, anthropomorphic phantom and lung phantom in supine and prone positions, respectively, then design treatment plans and delivery those plans. Compare and analyze the radiation accuracy of the two different positions with E2E software.Results The cervical vertebra tracking accuracy in supine and prone positions is 0.77 and 0.87 mm, respectively, with a difference of 0.01 mm; for thoracic vertebra tracking, the accuracy is 0.78 and 0.76 mm, respectively, with a difference of 0.02 mm; for lumbar vertebra, 0.89 and 0.80 mm, respectively with a difference of 0.09 mm; and for sacral vertebrae, 1.90 and 2.27 mm, with a difference of 0.37 mm.Conclusion For the three static phantoms, the differences of spine tracking accuracy between supine and prone position setups are very small. Therefore the accuracy in the two different positions can be considered equal.
  • Assessment of Radionuclide Level in Soil Samples for Partial Areas of Hainan, China
    LI Wen-hong, ZHOU Qiang, ZHANG Jing, ZHANG Qing, XU Cui-hua, TUO Fei
    2016, 25(2): 136-139.
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    Objective To evaluate the level of radioactivity in soil samples in some area of Hainan.Methods During 2012, topsoil samples were collected from China's Hainan Province, in order to evaluate their radioactivity. The radioactivities of 15 soil samples have been measured with a low-background high-purity germanium gamma spectroscopy.Results In the samples,the average activity concentrations of 226Ra, 232Th and 40K were (26.3±1.0),(23.7±0.9) and (366.1±13.4) Bq·kg-1, respectively. And the activity concentration of 137Cs was found to vary from < 0.35 (minimum detectable activity concentration) to 2.25 Bq·kg-1. By using the results of 226Ra, 232Th and 40K in the sampled soils, the average outdoor gamma dose rate in air was calculated as(41.7±1.5) nGy·h-1. Furthermore, the average outdoor annual effective dose from terrestrial radiation was 0.05 mSv.Conclusion The results of soil sample analysis show that the measurement results of all the points are normal.
  • Analysis of Operators' Eye Lens Dose in Common Interventional Operation
    MAO Xue-song, LI Hai-liang, LI Jie-qing, LI Quan-tai, ZHU Jian-guo
    2016, 25(2): 140-142.
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    Objective To estimate the Operators'Eye Lens dose in Common Interventional Operation.Methods Common interventional operations (Cerebral angiography,Coronary angiography,TACE,angiography of the Lower extremity). Was chosen before the surgery,put the prepared thermoluminescence dosimeter near the left edge of the surgeon's surgical cap,and then we measure the dose.Results The eye lens dose is different in different types of operation,the highest is coronary stent implantation, the dose of the first performer is (40.38±42.40) μGy,and the second one is (63.73±61.72) μGy; In one operation,the second performer's eye lens dose is always higher than the first one; In the same kind of operation,there is a positive linear correlation between eye lens dose and the exposure time with the correlation coefficient of r=0.469,P< 0.01.Conclusion The performer'eye lens receive a cevtain amount of dose of radiation in surgical intervention,but there is a low rate of wearing lead glasses,so we should pay more attention to eye protection,strengthen protection management,minimize the radiation exposure.
  • The Impact Lessons and Lessons Impact of Japan's Fukushima Nuclear Accident in Nearly Four Years Later
    WANG Yan-jun, LI Wen-hong, DENG Jun, MA Jian-feng, LIU Qiang, GAO Ling
    2016, 25(2): 143-145,149.
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    Objective To discuss the impact and lessons of Japan's Fukushima nuclear accident in nearly four years.Methods Fukushima nuclear accident induced by the tsunami triggered earthquake in 2011 in Japan. This accident was the second accident of history followed the Chernobyl nuclear accident which was rated as the seventh nuclear accident.Results After the Fukushima nuclear accident, external irradiation dose rate in environment increased, which mainly resulted from leakage of 134Cs and 137Cs in Fukushima nuclear accident, meanwhile 131I also was detected in human breast milk. The activity of 131I and 137Cs which are the most harmful to people and the environment ranged from 100 to 500 PBq and from 6 to 20 PBq, respectively. Further study found that there were chromosome aberration rate increased dramatically in spleen lymphocyte of Apodumus argenteus and Mus Mmusulus in moderate and high pollution districts in Fukushima prefecture.Conclusion Fukushima nuclear accident in nearly four years has a huge influence on human beings health, other biology and environment. A lot of lessons should be learned, for example, staf leave, health administration, information communication and post-disaster reconstruction.
  • The Radioactivity Levels and Population Doses in Areas around Haiyang Nuclear Power Plant before Operation
    LIU Ya-qi, ZHANG Wei, LI Qun-wei, YU Xi-rong
    2016, 25(2): 146-149.
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    Objective To analyze the radioactivity levels and obtain the baseline value of radionuclide in the food in the area around the Haiyang Nuclear Power Plant, and to provide a basis for assessing the impact of the nuclear power station on the population.Methods To collect 22 kinds of food samples of daily consumption diet around the nuclear power plant in the 50 km area, calculate the activity concentration (Bq/kg) by using the efficiency curve method, and estimate the committed effective dose of the local population.Results The natural radionuclides 40K, 238U, 232Th, 226Ra and artificial radionuclides 137Cs and 60Co were detected in food samples. The artificial radionuclides were just above the detectable limit. Other artificial radionuclides just like 131I、134Cs、58Co were not detected. The average radioactivity of 40K、238U、232Th、226Ra、137Cs were 12.858、0.550、0.146、0.077、0.016 Bq/kg,their range were 0.0266~2.2736,0.0013~1.3599,0.0127~0.2568,0.0043~0.0555,0.0065~0.0065,2.433~30.4572 Bq/kg respectively. The average radioactivity decreased in 40K、238U、232Th、226Ra、137Cs and 60Co in regular order. The committed effective dose of all radionuclides are 39.21μSv/a among which the artificial radionuclide part is 0.03 μSv/a.Conclusion No artificial radionuclides were detected except trace amounts of 137Cs and 60Co in the surrounding areas of Haiyang Nuclear Power Plant. The concentrations of all radionuclides in food are lower than the national standard limits which will lead a little dose burden.
  • A Preliminary Study on the Relationship between Measured Time and the Minimum Detectable Concentration (MDC) of Samples during Radioactivity Measurement of Food and Drinking-water
    YAO Shuai-mo, ZHANG Qing, ZHOU Qiang, ZHANG Jing, LI Wen-hong, TUO Fei
    2016, 25(2): 150-153.
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    Objective To compare the MDC of radionuclides in food and drinking-water achieved by different measured time, and to provide reference material to deal with a nuclear or radiological emergency.Methods Measuring the MDC of radionuclides in Marinelli backer filled with samples which are drinking-water, milk and fresh spinach by the measured live time 2 hours, 4, 8, 12, 24 and 72 hours, respectively, then comparing the results with the values of operational intervention level 6 (OIL6) recommended by International Atomic Energy Agency (IAEA) and the guidelines for drinking-water quality recommended by World Health Organization (WHO).Results The MDC of the samples of drinking-water and milk are in the range of 0.04~0.30 Bq/kg, 0.05~0.34 Bq/kg and 0.05~0.36 Bq/kg for the 131I, 137Cs and 134Cs if measure them from 2 to 72 hours, but the MDC of the sample of fresh spinach is a little higher than that of drinking-water and milk. All the MDC we got are in conformity with the relevant standards, and the longer time we spent in measuring samples, the smaller MDC we would get.Conclusion In the condition of time permitting, we could take a longer measured time to improve the detectability, but in an emergency a cost-benefit analysis to choose the most suitable time to match the MDC is necessary.
  • Experimental Study on X-ray Radiation Influence on the Lipid Peroxidation and Free Radicals Metabolic Effects of Body's
    LI Da-peng, WANG Yong-qing, LV Chun-lei, WANG Feng-jiao, ZHENG Wen-zhe
    2016, 25(2): 154-156,160.
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    Objective To study X-ray radiation effect on the body's lipid peroxidation and metabolic effects of free radicals.Methods 30 Wistar rats without specific pathogens,were randomly and averagly divided into experimental group (A), experimental group (B), the control group (C), the A, B group rats were daily with whole-body-one-time X-ray irradiated for 6 days consecutively, collected,A group radiation dose is 3 Gy, B group radiation dose is 2 Gy, C group receives no radiation. After the completion blood specimens of survival rats were malondialdehyde(MDA) and superoxide dismutase(SOD) and hydrogen peroxide enzyme(CAT) in serum were deteted for 3 group rats for analyse.Results MDA:A group were higher than C group,B group were higher than C group,A group were higher than B group. There were no statistically significant difference between the groups in MDA detection(P> 0.05). SOD:The difference between A and C group was statistically significant(P< 0.05). The difference between A and B group was statistically significant(P< 0.05). The difference between B and C groups has no statistically significance(P> 0.05),while the level of SOD for A group were significantly below than C group,and A group were significantly below than B group; CAT:The difference between A and C group was statistically significant(P< 0.05). The difference between A and B group has no statistical significantce(P< 0.05). The difference between B and C groups has no statistical significantce(P> 0.05),while the level of CAT for A group were significantly below than C group,and A group were significantly below than B group.Conclusion X-ray radiation has significant influence on the SOD and CAT. The significantly reduce the activity of serum SOD and CAT, the antioxidant enzyme of SOD and CAT was anticorrelation with irradiation dose, which can improve the level of serum MDA, and there was no significant influence to the level of MDA.
  • Preliminary Preparation of 177Lu-Labeled Rituximab
    MA Xiu-feng, ZHANG Jun-li, Li Hong-yu, GAO Shuai, DU Jin
    2016, 25(2): 157-160.
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    Objective For confirming the optimal labeling condition, Rituximab was conjugated to two bifunctional chelating agents (p-SCN-Bz-DOTA and p-SCN-Bz-DTPA), and the conjugates were radiolabeled with 177Lu.Methods Rituximab was conjugated to the chelating agents, then the conjugates were radiolabeled with 177Lu. The amount of antibody, nuclide and buffer were fixed, this work emphasized the investigation of PH, reaction time, temperature and the amount of chelating agents.Results conjugates were obtained with labeling yield between 3% to 99.9% at different labelling conditions, the preliminary work demonstrated that the optimum labeling conditions were the reaction molar ratio of monoclonal antibody and chelating agent was 1:100, pH=6.0~7.0, reacting at 40℃ for 30 min.Conclusion Conjugates were obtained with labeling yield and radiochemical purity higher than 99% at optimum labelling conditions, it could be suitable for clinical research.
  • Compare the Degree of Injury of BALB/c Mouse Radiation-Induced Skin Damage after Irradiating Different Doses of X-ray
    GAO Hong-lin, ZHANG Yu-min, CHU Li-ping, SONG Na-ling
    2016, 25(2): 161-162,166.
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    Objective To study BALB/c mouse acte radiation skin damage caused by different doses of X-ray to provide experimental evidence for the establishment of animal acute radiation skin injury model in the fundamental research field.Methods Adopt Rs2000 biological X-ray irradiator which features high uniformity of dosage and safety to irradiate lower limbs of BALB/c respectively for 40、50、60 Gy, after the establishment of skin injury model, observe mice condition every five day and do injury severity score, and compare skin pathological changes of different mice through H&E staining.Results BALB/c mice are susceptible to radiation, the skin damage symptoms came to exist about 10 days after irradiation, skin of mice in 50、60 Gy groups did not deteriorate after 32 days, while skin damage was still continuing in 40 Gy group.Conclusion It was easier for BALB/c mice to accquire a better acute radiation-induced skin damage model at a dosage of 40 Gy.
  • Study on Guidance Levels for Radionuclides in Drinking Water
    JU Jin-xin, XUE Ru, CHEN Er-dong
    2016, 25(2): 163-166.
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    Objective To provide appropriate advice for setting up the guidance levels for radionuclides in drinking water and developing standards for drinking water.Methods With comparing the WHO and EU's rationale and application of the guidance levels for radionuclides in drinking water, and combining the current standards in China and the research results at home and abroad, analyze and discuss the development of the standard for the guidance levels and relative analytical methods for radionuclides in drinking water.Results The guidance levels for radionuclides in drinking water should be calculated using the individual dose criterion, dose coefficient for ingestion by adults and annual ingested volume of drinking-water. With regard to the results of the relative investigations and researches in China. The standards of the analytical methods should be revised.Conclusion The standards for drinking water should be improved with developing the standards of guidance levels for radionuclides in drinking water and the relative analytical methods.
  • Dose Estimation to Landfill Disposal Worker for Very Low Level Radioactive Waste
    WU Xiao-yan, GU Xiao-na, MA Yue-feng, XUE Xiang-ming, ZHAN Jing-ming
    2016, 25(2): 173-175.
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    Objective To estimate the personal dose of the worker who are engaged in treating the very low level radioactive solid waste landfill and test dose whether or not their annual effective can meet the requirements of enterprisemanagement target value.Methods According to the estimation model from "Landfill disposal for very low level radioactive waste"(GB/T 28178-2011), the external irradiation and Inhalation exposure dose were estimated.Results The conservative estimation of the landfill plant workers'annual effective dose is 0.86mSv.Conclusion During the the very low level radioactivesolid wastereceived,the key-workers have no radiation hazard.
  • Investigation and Analysis of the Medical Imaging Department Undergraduates' Cognitive Status about X-ray Radiation Protection
    WANG Ling-sheng, WU De-hong, ZHAO Yun, WANG Kai-hua
    2016, 25(2): 178-180.
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    Objective To acquire the medical imaging department undergraduates' cognitive level of X-ray radiation protection knowledge, provide reference basis for radiation protection courses, to promote standardization, rationalization and optimization for the clinical imaging tests, so as to reduce the X-ray damage to the lowest level.Methods An anonymous questionnaire survey was conducted among 165 medical imaging department undergraduates of year 2011 from Hubei Medical College.Results The medical imaging department undergraduates have a low level of attention to radiation protection knowledge, and the mastery of the knowledge of radiation protection is not comprehensive, lack of formal way of radiation knowledge education.Conclusion medical colleges should attach importance to radiation protection knowledge education, actively carry out relevant radiation courses, and improve the knowledge of radiation protection for future medical work and disaster relief.
  • Radiation dose Analysis of X-ray Luggage Inspection System in Chengdu Subway Stations
    PAN Xing-ping, RAN Long-ju, LU Xiao-qing, TU Jun, TU Cheng
    2016, 25(2): 182-183,186.
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    Objective To evaluate the status of radiological protection of X-ray luggage inspection system in subway stations,in order to provide basic data for radiological health protection and management and provide basic countermeasure of protecting the effecton health of inspectors and the public during operation.Methods The detection was carried out according to the Radiological protectionstandards for X-ray luggage inspection system (CBZ 127-2002).Results Chengdu subway stations currently include the use of two kinds of models of the X-ray luggage inspection system air kerma rate levels in luggage entry side as the highest (average 0.48 μGy/h), the highest for 1.36 μGy/h; Second for luggage export side (average 0.27 μGy/h) peaks at 0.45 mu Gy/h, system outside surface, and other basic channels and passenger security personnel operation area close to the background radiation level.Conclusion The status of radiological protection of subway Stations X-ray luggage inspection systems are good in Chengdu,and the leakage radiation levels meet the national standards. Under normal operating conditions,this system can not damage the health and safety of inspectors and the public.
  • Effect of Target/Filter Combination on Radiation Dose in Digital Mammography
    LI Yun, DENG Da-ping
    2016, 25(2): 191-193.
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    Objective To discuss the effect of different target/filter combinations (Mo/Mo、Mo/Rh、W/Rh) on radiation dose in digital mammography. Chose optimal exposure parameters was so important to ensure image quality and reduce radiation injury.Methods First peform strict quality control on mammography before experiment. The same exposure conditions, pressure, compression thickness, and different target/filter combinations were employed under the AOP and Manual exposure modes. Record the target/filter combination for each exposure and read the entrance surface dose(ESD) on Ray Safe. Calculate average glandular dose(AGD) and the means. One-way analysis of variance and SPSS 17.0 were used in statistical analysis.Results AGD values which were acquired in the phantom with different thickness and three different target/filter combinations were statistically different. The AGD values of were always the lowest for W/Rh but highest for Mo/Mo. With the increase of phantom thicknesses, the AGD values which were acquired with Mo/Mo, Mo/Rh, and W/Rh target/filter combinations were increased.Conclusion W/Rh combination for 10~70 mm phantom thicknesses which respectively can reduce the radiation dose, were the optimal choose of three different target/filter combinations, also they can provide the best image quality with lowest radiation dose.
  • Control Effect of Occupational Hazards in 25 Construction Projects of Radiodiagnosis and Radiotherapy of Private Hospital in Quanzhou City in 2013
    PENG Yan-lan, PAN Bao-zhong, TANG Xue-ping
    2016, 25(2): 201-202,205.
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    Objective To analyze evaluation situations of occupation hazard control effectiveness of 25 radiodiagnosis and radiotherapy construction projects of private hospital in Quanzhou city in 2013,find the existed problems and defects,explore the solutions and strategies which could provide a scientific basis for radiation protection management.Methods Through survey on the spot hygienics, Radiological protection detection, and according to the national radiological methods of the relevant laws, regulations and standards, analysis of reports of Control effect of occupational hazards in 25 construction projects of radiodiagnosis and radiotherapy of private hospital completed in 2013.Results 25 reports had been Completed in 2013. Among these 25 reports, the best was Radiological protection detection, the percent of pass was 100%; Followed by project site selection, layout, room area and ventilation, work lights, education training, pass rate was more than 80%; Other protective measures had more defects and the qualified rate is low.Conclusion Private hospital on radiological protection work in Quanzhou city overall is good, but there are also some deficiencies.
  • Status of Image Quality Control of Medical Diagnostic X-ray Equipment in Shanghai in 2014
    MIAO Dong-yue, WU Yu-xia, GAO Lin-feng, XIA Si-wei
    2016, 25(2): 203-205.
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    Objective To investigate the current situation of image quality control of medical diagnostic X-ray equipment in Shanghai, to ensure medical safety of the public.Methods The detection and evaluation were performed according to the current health industry standard in China. The data were statistically analyzed.Results Totally there were 116 medical diagnostic X-ray equipments in the sampling. The total qualified rate of image quality control was 81.03%. However, there was a great differences in qualified rate in different sub-groups of medical diagnostic X-ray equipment. The highest qualified rate was 100% in common X-ray imagescope, while the qualified rate of digital X-ray photographs and digital gastrointestinal machine was 85.71% and 87.50% respectively. And common X-ray photographs had a lowest rate of 50%, significantly lower than the former two.Conclusion The operation status of medical diagnostic X-ray equipment in Shanghai is satisfactory, but the detection and management of imaging quality control of medical X-ray diagnostic equipment should be strengthened so as to protect the safety and health of patients.
  • Kilovoltage Cone-Beam CT in the Evaluation of Set-Up Errors in the Nasopharyngeal Carcinoma with Intensity Modulated Radiotherapy
    MO Xiao-mi, XIAO Ai-nong, WU Hai-biao, QU Guo-pu, TAN Zhen-gan
    2016, 25(2): 206-208.
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    Objective To analyze the setup errors using Kilovoltage X-ray cone-beam CT imaging in nasopharyngeal carcinoma treated by intensity modulated radiotherapy.Methods 32 patients diagnosed with nasopharyngeal carcinoma and treated with IMRT were selected. Kilovoltage cone-beam scan was performed weekly before treatment. The setup errors on translational directions (X,Y,Z) were obtained by matching the CBCT images and the planning CT images.Results The average errors were(1.50±0.87) mm,(1.59±0.87) mm and(1.95±0.99) mm for right-left, head-feet and anteriority-posterior direction respectively. According to the Van Herk formula, PTV margins were 2.9 mm, 4.5 mm and 3.1 mm, respectively.Conlusion The results showed that the setup errors in anteriority-posterior direction were larger than in right-left and head-feet direction, which should be taken care during the patient daily setup.
  • The Boron Neutron Capture Therapy and the Dose Measuring Methods
    CAO Qin-jian, ZHENG Jian-guo, LIU Li-ye
    2016, 25(2): 221-224.
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    Objective To analyze the key point and solutions of the dose measurement through the describing development of the dose measurement for BNCT.Methods The problems of the dose measurement for BNCT were developed with the analysis of the development status, fundamentals, radiation dose components and dose measuring methods of BNCT.Results Dose measurement is important for the quality of BNCT. The dose of neutron and gamma ray was respectively determined with the integral and real-time measuring methods.Conclusion The difficulty of dose measurement for BNCT is to distinguish the dose of neutron and gamma, due to the n-γ mixture radiation field.
  • Development of A Distributed Emergency Monitoring System
    LI Hang, WANG Kai, CHEN Ling, YANG Hong-wei, LIU Yang, ZHANG Liang, XIONG Wen-jun
    2016, 25(2): 224-228.
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    Objective To improve the emergency response capability during a nuclear or radiation accident.Methods The detection units, which assembled the Geige-Muler tubes and NaI(Tl) spectrometers, can increase the dose rate measurement range and identify the nuclides real-timely. The monitoring data could be transferred to the monitoring station wirelessly by WCDMA or Radio Frequency module. The meteorological and geographical information could be integrated into the system software, which can provide the real-time dose rate, the contaminated distribution, and even deducing the release activity.Results The detection unit is light-weight and robust, which can be easily distributed to the accident scene and provide real-time information.Conclusion The experiment results show that the Distributed Emergency Monitoring System (DEMS) is intended to be a one-stop service on nuclear and radiation emergency decision making.
  • Crotonaldehyde Exposure on Male Rat Liver Injury Research
    JIA Qi-xiang, JIA Qiang, SHAN Yong-le, ZHANG Zhi-hu
    2016, 25(2): 229-232.
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    Objective To investigate the crotonaldehyde exposed liver injury in male rats.Methods 40 healthy male Wistar rats were randomly divided into 4 groups:high dose group, middle dose group, low dose group and control group, with 10 rats in each group. Rats in each group were randomly divided into groups. Crotonaldehyde oral gavage were given high dose group 8.44 mg/kg, middle dose group 4.22 mg/kg, low dose group 2.11 mg/kg, rat irrigation gastric volume was 1ml/100g weight. Once every day, the animals were sacrificed after 28 d continuous exposure. Biochemical test was done of the peripheral blood; ELISA method was used for the detection of serum malondialdehyde (MDA), superoxide dismutase (SOD), glutathione peroxidase (GSH PX) activity; rat organs was weighted and calculated the organ coefficient, the routine hematoxylin and eosin staining produced pathological specimens for observing the liver tissue pathological changes.Results Compared with the control group, high dose group rats body weight decreased, liver index increased significantly, and as the dose increased, the liver coefficient increased; serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels significantly increased whilein high dose group and middle dose group, MDA content increased; the content of SOD decreased; the content of GSH-PX decreased in high dose group, the differences were statistically significant (P< 0.05); compared with the control group, the total bilirubin heart coefficient, speen index, kidney index and serum (TBIL), urea (BUN), uric acid (UA), creatinine (CRE), glucose (GLU), triglyceride (TG), total cholesterol (CHOL) levels had no significant change, the difference was not statistically significant (P> 0.05); the pathological sections showed that liver tissue of rats with inflammatory injury.Conclusion Exposure to crotonaldehyde, liver injury was found in male rats.
  • PET/CT Features of the Bone Marrow in the Radiation Field after Radiation Therapy
    FU Zheng, ZHOU Jing, GUO Yan-luan, LIU Wei
    2016, 25(2): 233-236.
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    Objective To investigate the characters and the clinical value of PET/CT in the radiation field after radiation therapy.Methods PET/CT was performed in both the cancer patients (32) after radiation therapy and normal healthy people (32). The SUV characters of the bone marrow of the radiation field between 32 patients after radiation therapy and the normal healthy patients were compared.Results The bone marrow uptake of FDG after radiotherapy is significantly less than the normal.Conclusion The change of FDG PET/CT of the bone marrow in the radiation field is distinctive after radiation therapy, which may guide the treatment of cancer.
  • Therapeutic Effect of Early Postoperative Radiotherapy after Keloidectomy
    ZHANG Rong-xin, CAO Yong-zhen, ZHANG Wen-xue, HU Jian-zhong
    2016, 25(2): 237-239.
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    Objective To evaluate the Therapeutic effect of early postoperative radiotherapy after keloidectomy.Methods Retrospective analysis was performed on 128 lesions in 121 patients from Jan 2005 to Dec 2014 and radiotherapy was given in 24h after operations. The age ranges from 12 to 74 years old. Vertical exposure with 5 MeV electron-beam was adopted one time every other day. The dosage of radiotherapy was 400 cGy every time, total 4 times. Treatment fields including entire keloid scars, and any suture holes with l cm-margin around the lesion were used. 5mm tissue compensator was placed on the surface of the skin. The total dose is 16 Gy. The follow-up begun periodically after the treatment.Results In all the cases, 78 lesions(60.9%) were cured,31 lesions(24.2%) were effective,4 lesions(3.1%) were of no avail,15 lesions(11.7%) relapsed. The total effect rate was 85.1%.Conclusion High-energy electron-beam radiotherapy for keloids in 24h after keloidectomy have good therapeutic effect in preventing keloid from recurrence, with rare early toxicity and late toxicity.
  • The Diagnostic Value of Spiral CT Scan in Cervical Lymph Node Metastasis of Laryngeal Carcinoma and Hypopharyngeal Carcinoma
    TIAN Geng, ZHENG Jing-zhen
    2016, 25(2): 240-242.
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    Objective To explore the application value of spiral CT scan in cervical lymph node metastasis of laryngeal carcinoma and hypopharyngeal carcinoma.Methods Randomly selected 46 consecutive hospitalized patients with laryngeal carcinoma and hypopharyngeal carcinoma between January 2014 and January 2015 as the research object. All the patients were diagnosed as laryngeal carcinoma and hypopharyngeal carcinoma by pathological experiments after operations. 21 patients were diagnosed as cervical lymph node metastasis. All the patients were examined by spiral CT before operations. And compared the pathological results with the spiral CT's pathological stage of laryngeal carcinoma and hypopharyngeal carcinoma and diagnosis of cervical lymph node metastasis.Results In CT, there was little difference between the result of preoperative T staging and postoperative T staging of laryngeal carcinoma and hypopharyngeal carcinoma. (P> 0.05) And it was not statistically significant. There was little difference between the detection rates of cervical lymph node metastasis in CT and the postoperative pathological results. (P> 0.05) In enhanced spiral CT, we could see the enlargement of lymph nodes of 21 cases with cervical lymph node metastasis in different levels. And the lymph nodes in 18 cases merged into groups irregularly and lobulatedly. The boundaries of lymph nodes were blurred and adhesive with the surrounding tissues. Besides, the central parts of the lymph nodes were low density necrosis areas or ringlike intensify.Conclusion Spiral CT examination before the operation can accurately evaluate the pathological staging of patients and also have a high detection rate of the lymph node metastasis, which has values on clinical application and promotion.
  • Effects of Different Doses of Atorvastatin on the Prognosis of Patients with STEMI After PCI
    LI Hui-ying, GUO Xin-zhong, LI Jing, XU Xia
    2016, 25(2): 242-245.
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    Objective To investigate the effect of different doses of atorvastatin on the prognosis of patients with STEMI after PCI.Methods A total of 118 patients with acute STEMI were selected and then randomly divided into two groups. The observation group(n=60) was given atorvastatin 40mg/day after PCI and 20mg/day after one months. The control group(n=58) was given atorvastatin 20 mg/day after PCI. The changes were observed of creatine kinase MB, cardiac troponin I and high-sensitivity C-reactive protein in 8 hours after PCI and 24 hours after PCI. After 1 months of follow-up, the primary end point events were recorded.Results The CK-MB, cTnI and hs-CRP in the two groups were significantly higher in 8 hours after PCI and 24 hours after PCI than those in the preoperative PCI(P< 0.05). The levels of CK-MB, cTnI and hs-CRP in the observation group were significantly lower than those in the control group(P< 0.05). Compared with the control group, the incidence of the primary endpoint events in the observation group was statistically significant(P< 0.05) after 1 months follow up.Conclusion The treatment of atorvastatin in the patients with STEMI after PCI can significantly reduce the incidence of major adverse cardiovascular events.
  • The Exploration of the Application of Large Digital Flat Panel X-ray Machine and Digital Radiography in Diagnosis of Small Gastric Ulcer
    MAO Song-wei, CHEM Ying-min
    2016, 25(2): 246-247,250.
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    Objective To explore the application of digital flat detection x-ray machine and direct radiography in the diagnosis of small gastric ulcer.Methods We followed up to collect gastric ulcer cases confirmed by endoscopy and having reccived the barium examination. Form August 2011 to August 2013 55 cases for flat panel detection x-ray machine and digital fluoro radiography were reguarded as the observation group. Form September 2013 to September 2015 82 cases were regarded as the control group since we have carried out flat panel detection x-ray machine and digital radiography in our department. We analyzed comparatively the results.Results The diagnosis rate of gastric ulcer in direct radiography was higher than that of it in digital fluoro radiography for digital large flat panel detection x-ray machine. (P< 0.05).Conclusion The digital flat panel detection x-ray machine and digital radiography can better display small gastric ulcer, improve lesion detection rate, decrease the misdiagnosis and missed diagnosis, help radiologists to make a correct diagnosis and provide a reliable basis for clinical treatment.