JIANG Shi-quan, YE Fei, SU Shi-jie, et al
2001, 10(2): 67-68.
The radioprotective effect of polysaccharides of Huangmo (PSH) and its effects on LPO content and SOD、GSH-PX and CAT activities of liver in irradiated mice were studied.The results showed that the 30-day survival rate of mice after 8.0 Gy X-ray irradiation increased significantly when the mice were injected with PSH before irradiation, and the survival days were delayed, the protection index was 1.32.Meanwhile, the effect of PSH was similar to polysaccharides of Ginseng (PSG).We in our further study found that PSH lowered LPO content in the liver of mice 72h after 8.0 Gy X-irradiation, and increased the activities of SOD、GSH-P and CAT.The results suggest that PSH has an obvious radioprotective effect, and its possible mechanism is that PSH may be a scavenger of free radicals, and can suppress or stop the reactions of lipid peroxidation.